EDMM

General

Type : Organophosphate,Sulfur Compound,Organothiophosphate,Nerve Agent V-series

Chemical_Nomenclature : O-ethyl S-(2-dimethylaminoethyl) methyl phosphonothioate

Canonical SMILES : CCOP(=O)(C)SCCN(C)C

InChI : InChI=1S\/C7H18NO2PS\/c1-5-10-11(4,9)12-7-6-8(2)3\/h5-7H2,1-4H3

InChIKey : PKDYQTANBZBIRM-UHFFFAOYSA-N

Other name(s) : Medemo,25 SN,33 SN,NISTC20820808,BRN 1769425,O-Ethyl S-2-dimethylaminoethyl methylphosphonothiolate,4-04-00-03519,S-[2-(Dimethylamino)ethyl] o-ethyl methylphosphonothioate,O-Ethyl-S-(2-dimethylaminoethyl)-methylphosphonothioate,O-Aethyl-S-(2-dimethylaminoaethyl)-methylphosphonothioat

MW : 211.26

Formula : C7H18NO2PS

CAS_number : 20820-80-8

PubChem : 102302

UniChem : PKDYQTANBZBIRM-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

References (11)

Title : The influence of inhibitors and other factors on cholinesterases - Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5

Author(s) : Bajgar J

Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 34 :5 , 1991

Abstract : Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5

ESTHER : Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5

PubMedSearch : Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5

PubMedID: 1759111

Title : Inhibition of multiple molecular forms of human brain acetylcholinesterase by different types of inhibitors - Bajgar_1989_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_32_425

Author(s) : Bajgar J , Mate L

Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 32 :425 , 1989

Abstract : Bajgar_1989_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_32_425

ESTHER : Bajgar_1989_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_32_425

PubMedSearch : Bajgar_1989_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_32_425

PubMedID: 2637489

Title : Anticholinergic action of cholinesterase reactivator methoxime (bis-\/4- hydroxyaminomethylpyridinium\/-methane dichloride) -

Author(s) : Jakl A , Fusek J , Bajgar J

Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 29 :457 , 1986

PubMedID: 3481651

Title : Some possibilities of protection against acetylcholinesterase inhibition by organophosphates in vivo -

Author(s) : Bajgar J , Patocka J , Fusek J , Hrdina V

Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 27 :425 , 1984

PubMedID: 6599819

Title : The influence of some drugs on the rat blood phosphodiesterase activity -

Author(s) : Bajgar J , Fusek J , Patocka J , Hrdina V

Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 26 :423 , 1983

PubMedID: 6100335

Title : Protective effect of 9-amino-7-methoxy-1,2,3,4-tetra-hydroacridine against inhibition of acetylcholinesterase by O-ethyl s-(2- dimethylaminoethyl) methylphosphonotioate in vivo -

Author(s) : Bajgar J , Fusek J , Patocka J , Hrdina V

Ref : Archives of Toxicology , 54 :163 , 1983

PubMedID: 6651529

Title : [Therapy of domestic animals affected by alkylphosphates] - Benes_1979_Vet.Med_24_623

Author(s) : Benes J , Hrusovsky J , Proksova M

Ref : Vet Med , 24 :623 , 1979

Abstract : Benes_1979_Vet.Med_24_623

ESTHER : Benes_1979_Vet.Med_24_623

PubMedSearch : Benes_1979_Vet.Med_24_623

PubMedID: 117593

Title : Actions of O-ethyl-S-(2-dimethylaminoethyl)-methylphosphonothioate and some pyridine aldoximes on isolated guinea-pigs heart atria - Fusek_1978_Acta.Biol.Med.Ger_37_347

Author(s) : Fusek J , Patocka J , Bajgar J

Ref : Acta Biologica et Medica Germanica , 37 :347 , 1978

Abstract : Fusek_1978_Acta.Biol.Med.Ger_37_347

ESTHER : Fusek_1978_Acta.Biol.Med.Ger_37_347

PubMedSearch : Fusek_1978_Acta.Biol.Med.Ger_37_347

PubMedID: 706945

Title : [Therapy of organophosphate poisoning in animals] - Benes_1976_Vet.Med_21_343

Author(s) : Benes J , Proksova M , Hrusovsky J

Ref : Vet Med , 21 :343 , 1976

Abstract : Benes_1976_Vet.Med_21_343

ESTHER : Benes_1976_Vet.Med_21_343

PubMedSearch : Benes_1976_Vet.Med_21_343

PubMedID: 826002

Title : [Antidotal effect of TMB-4(Trimedoxime) compos. Spofa in sheep intoxicated with O-ethyl S-(2-dimethylaminoethyl) methyl phosphonothioate]. [Czech] - Benes_1976_Vet.Med_21_237

Author(s) : Benes J , Proksova M , Hrusovsky J

Ref : Veterinarni Medicina , 21 :237 , 1976

Abstract : Benes_1976_Vet.Med_21_237

ESTHER : Benes_1976_Vet.Med_21_237

PubMedSearch : Benes_1976_Vet.Med_21_237

PubMedID: 824781

Title : [Reactivating effect of trimedoxime and obidoxime on cholinesterases inhibited in the heart and intercostal muscles of the rat during acute poisoning with O-ethyl-S-(dimethylaminethyl)-methylthiophosphonate. (A histochemical study)]. [Czech] -

Author(s) : Picha B

Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 17 :195 , 1974

PubMedID: 4620479

EDMM

General

Target

References (11)

1. The influence of inhibitors and other factors on cholinesterases

2. Inhibition of multiple molecular forms of human brain acetylcholinesterase by different types of inhibitors

3. Anticholinergic action of cholinesterase reactivator methoxime (bis-\/4- hydroxyaminomethylpyridinium\/-methane dichloride)

4. Some possibilities of protection against acetylcholinesterase inhibition by organophosphates in vivo

5. The influence of some drugs on the rat blood phosphodiesterase activity

6. Protective effect of 9-amino-7-methoxy-1,2,3,4-tetra-hydroacridine against inhibition of acetylcholinesterase by O-ethyl s-(2- dimethylaminoethyl) methylphosphonotioate in vivo

7. [Therapy of domestic animals affected by alkylphosphates]

8. Actions of O-ethyl-S-(2-dimethylaminoethyl)-methylphosphonothioate and some pyridine aldoximes on isolated guinea-pigs heart atria

9. [Therapy of organophosphate poisoning in animals]

10. [Antidotal effect of TMB-4(Trimedoxime) compos. Spofa in sheep intoxicated with O-ethyl S-(2-dimethylaminoethyl) methyl phosphonothioate]. [Czech]

11. [Reactivating effect of trimedoxime and obidoxime on cholinesterases inhibited in the heart and intercostal muscles of the rat during acute poisoning with O-ethyl-S-(dimethylaminethyl)-methylthiophosphonate. (A histochemical study)]. [Czech]