Lycocasuarine-C

IC50 AChE 0.24 +/-0.03 BChE 1.82 +/- 0.12 microM

General

Type : Derivative of Huperzine,Natural

Chemical_Nomenclature :

Canonical SMILES : C1(NC2=C(C=C1)[C@]34[C@@H](C(C2)C=C(C3)C)C(C([N+]4(C)[O-])=O)CO)=O

InChI : InChI=1S\/C17H20N2O4\/c1-9-5-10-6-13-12(3-4-14(21)18-13)17(7-9)15(10)11(8-20)16(22)19(17,2)23\/h3-5,10-11,15,20H,6-8H

InChIKey : DVCLJMAFRIENKG-XOCRXOJUSA-N

Other name(s) : lycocasuarine C

MW : 316.35

Formula : C17H20N2O4

CAS_number :

PubChem :

UniChem : DVCLJMAFRIENKG-XOCRXOJUSA-N

IUPHAR :

Wikipedia :

Target

Families : Lycocasuarine-C ligand of proteins in family: ACHE

Stucture :

Protein : human-ACHE

References (1)

Title : Lycodine type alkaloids from Lycopodiastrum casuarinoides with cytotoxic and cholinesterase inhibitory activities - Qu_2018_Fitoterapia_131_86

Author(s) : Qu SM , Shan BH , Wang HT , Wang S

Ref : Fitoterapia , 131 :86 , 2018

Abstract : Qu_2018_Fitoterapia_131_86

ESTHER : Qu_2018_Fitoterapia_131_86

PubMedSearch : Qu_2018_Fitoterapia_131_86

PubMedID: 30352296

Lycocasuarine-C

General

Target

References (1)

1. Lycodine type alkaloids from Lycopodiastrum casuarinoides with cytotoxic and cholinesterase inhibitory activities