Myricitrin-5-methyl-ether

Natural gastric lipase inhibitor from star anise. Monomethoxyflavone. 5-methyl ether derivative of myricitrin. Isolated from Rhododendron yedoense var poukhanense

General

Type : Flavonoid,Lipase inhibitor

Chemical_Nomenclature : 7-hydroxy-5-methoxy-3-[(2~{S},3~{R},4~{R},5~{R},6~{S})-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one

Canonical SMILES : CC1C(C(C(C(O1)OC2=C(OC3=CC(=CC(=C3C2=O)OC)O)C4=CC(=C(C(=C4)O)O)O)O)O)O

InChI : InChI=1S\/C22H22O12\/c1-7-15(26)18(29)19(30)22(32-7)34-21-17(28)14-12(31-2)5-9(23)6-13(14)33-20(21)8-3-10(24)16(27)11(25)4-8\/h3-7,15,18-19,22-27,29-30H,1-2H3\/t7-,15-,18+,19+,22-\/m0\/s1

InChIKey : LPVCLSBWFKENQA-FDNTWFBCSA-N

Other name(s) : Myricitrin-5-methyl ether,CHEBI:66423


MW : 478.40

Formula : C22H22O12

CAS_number :

PubChem : 70697818

UniChem : LPVCLSBWFKENQA-FDNTWFBCSA-N

IUPHAR :

Wikipedia :

Target

Families : Myricitrin-5-methyl-ether ligand of proteins in family: Acidic_Lipase

Stucture :

Protein : human-LIPF

References (1)

Title : Identification of a new natural gastric lipase inhibitor from star anise - Kamoun_2019_Food.Funct_10_469
Author(s) : Kamoun J , Rahier R , Sellami M , Koubaa I , Mansuelle P , Lebrun R , Berlioz-Barbier A , Fiore M , Alvarez K , Abousalham A , Carriere F , Aloulou A
Ref : Food Funct , 10 :469 , 2019
Abstract : Kamoun_2019_Food.Funct_10_469
ESTHER : Kamoun_2019_Food.Funct_10_469
PubMedSearch : Kamoun_2019_Food.Funct_10_469
PubMedID: 30632597
Gene_locus related to this paper: human-LIPF