Terbam

Lead compound for search of new insecticides with improved efficacy and specificity for AChEs of arthropod pests.

General

Type : Carbamate,Insecticide,tert-Butyl

Chemical_Nomenclature : (3-tert-butylphenyl) N-methylcarbamate

Canonical SMILES : CC(C)(C)C1=CC(=CC=C1)OC(=O)NC

InChI : InChI=1S\/C12H17NO2\/c1-12(2,3)9-6-5-7-10(8-9)15-11(14)13-4\/h5-8H,1-4H3,(H,13,14)

InChIKey : FSJYRLHKLVGCNH-UHFFFAOYSA-N

Other name(s) : Knockbal,TBPMC,Phenol, 3-(1,1-dimethylethyl)-, methylcarbamate,SCHEMBL78061,ZINC2031110,CHEMBL2046821


MW : 207.27

Formula : C12H17NO2

CAS_number : 780-11-0

PubChem : 13072

UniChem : FSJYRLHKLVGCNH-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : Terbam ligand of proteins in family: ACHE

Stucture :

Protein :

References (2)

Title : Mosquito Acetylcholinesterase as a Target for Novel Phenyl-Substituted Carbamates - Mutunga_2019_Int.J.Environ.Res.Public.Health_16_
Author(s) : Mutunga JM , Ma M , Chen QH , Hartsel JA , Wong DM , Ding S , Totrov M , Carlier PR , Bloomquist JR
Ref : Int J Environ Research Public Health , 16 : , 2019
Abstract : Mutunga_2019_Int.J.Environ.Res.Public.Health_16_
ESTHER : Mutunga_2019_Int.J.Environ.Res.Public.Health_16_
PubMedSearch : Mutunga_2019_Int.J.Environ.Res.Public.Health_16_
PubMedID: 31035318

Title : Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): construction, expression and biochemical properties of the G119S orthologous mutant - Temeyer_2014_Parasit.Vectors_7_577
Author(s) : Temeyer KB , Tong F , Totrov MM , Tuckow AP , Chen QH , Carlier PR , Perez de Leon AA , Bloomquist JR
Ref : Parasit Vectors , 7 :577 , 2014
Abstract : Temeyer_2014_Parasit.Vectors_7_577
ESTHER : Temeyer_2014_Parasit.Vectors_7_577
PubMedSearch : Temeyer_2014_Parasit.Vectors_7_577
PubMedID: 25491113
Gene_locus related to this paper: phlpp-m1f887