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Inhibitor Report for: WWL229

General
Type pNP, Carbamate, Piperidine
Chemical_Nomenclature (4-nitrophenyl) 2-(3-methoxypropyl)piperidine-1-carboxylate
Canonical SMILES COCCCC1CCCCN1C(=O)OC2=CC=C(C=C2)[N+](=O)[O-]
InChI InChI=1S/C16H22N2O5/c1-22-12-4-6-13-5-2-3-11-17(13)16(19)23-15-9-7-14(8-10-15)18(20)21/h7-10,13H,2-6,11-12H2,1H3
InChIKey XVBRVSAGMWRVCK-UHFFFAOYSA-N
Other name(s) Wwl229 ; 4-Nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate ; AOB2408 ; SYN5249 ; MolPort-039-138-796
________________________________________________________________________________________________
MW|322.36
Formula|C16H22N2O5
CAS_number|1338575-28-2
PubChem|72183487
UniChem|XVBRVSAGMWRVCK-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | WWL229 ligand of proteins in family: Carb_B_Chordata
Protein | human-CES3, mouse-Ces1d

References:
Search PubMed for references concerning: WWL229
    Title: A Unique Role of Carboxylesterase 3 (Ces3) in beta-Adrenergic Signaling-Stimulated Thermogenesis
    Yang L, Li X, Tang H, Gao Z, Zhang K, Sun K
    Ref: Diabetes, 68:1178, 2019 : PubMed

            

    Title: Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes
    Dominguez E, Galmozzi A, Chang JW, Hsu KL, Pawlak J, Li W, Godio C, Thomas J, Partida D and Saez E <6 more author(s)>
    Ref: Nat Chemical Biology, 10:113, 2014 : PubMed