p-nitrophenyl-N-butyl-carbamate

Also inhibits other serine hydrolases trypsine chymotrypsin scofield 1977

General

Type : pNP,Carbamate

Chemical_Nomenclature : (4-nitrophenyl) N-butylcarbamate

Canonical SMILES : CCCCNC(=O)OC1=CC=C(C=C1)[N+](=O)[O-]

InChI : InChI=1S\/C11H14N2O4\/c1-2-3-8-12-11(14)17-10-6-4-9(5-7-10)13(15)16\/h4-7H,2-3,8H2,1H3,(H,12,14)

InChIKey : LXLRTTHROGSMBS-UHFFFAOYSA-N

Other name(s) : n-butylcarbamic acid 4-nitrophenyl ester,CHEMBL558048,4-Nitrophenyl N-butylcarbamate,4-Nnbm,CTK5B8633,DTXSID60979440,BDBM50295663,4-Nitrophenyl hydrogen butylcarbonimidate,Carbamic acid, butyl-, 4-nitrophenyl ester,Carbamic acid,N-butyl-, 4-nitrophenyl ester


MW : 238.24

Formula : C11H14N2O4

CAS_number : 63321-50-6

PubChem : 3017401

UniChem : LXLRTTHROGSMBS-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : p-nitrophenyl-N-butyl-carbamate ligand of proteins in family: Cholesterol_esterase

Stucture :

Protein : pig-i3ltk9

References (2)

Title : p-Nitrophenyl and cholesteryl-N-alkyl carbamates as inhibitors of cholesterol esterase - Hosie_1987_J.Biol.Chem_262_260
Author(s) : Hosie L , Sutton LD , Quinn DM
Ref : Journal of Biological Chemistry , 262 :260 , 1987
Abstract : Hosie_1987_J.Biol.Chem_262_260
ESTHER : Hosie_1987_J.Biol.Chem_262_260
PubMedSearch : Hosie_1987_J.Biol.Chem_262_260
PubMedID: 3793726
Gene_locus related to this paper: pig-i3ltk9

Title : P-Nitrophenyl carbamates as active-site-specific reagents for serine proteases -
Author(s) : Scofield RE , Werner RP , Wold F
Ref : Biochemistry , 16 :2492 , 1977
PubMedID: 861216