[11C]N-methyl-tacrine
Reversible inhibitor of both AChE and BChE used in positron emission tomography (PET) imaging
General
Type : Acridine,Derivative of Tacrine,PET probe
Chemical_Nomenclature : [11C]N-methyl-tetrahydroamino-acridine
Canonical SMILES : CNC1=C2CCCCC2=NC3=CC=CC=C31
InChI : InChI=1S\/C14H16N2\/c1-15-14-10-6-2-4-8-12(10)16-13-9-5-3-7-11(13)14\/h2,4,6,8H,3,5,7,9H2,1H3,(H,15,16)\/i1-1
InChIKey : OBXGPCSAPSCKID-BJUDXGSMSA-N
Other name(s) : N-Methyltacrine,N-methyl-1,2,3,4-tetrahydroacridin-9-amine,Methyl-tacrine,N-Methyl-tha,Mtha-N,AC1L4U1Z,[11C]N-methyl-THA
MW : 211.29
Formula : C14H16N2
CAS_number :
PubChem : 192272
UniChem : OBXGPCSAPSCKID-BJUDXGSMSA-N
IUPHAR :
Wikipedia :
Target
References (2)
| Title : In vivo PET study of cerebral [11C] methyl- tetrahydroaminoacridine distribution and kinetics in healthy human subjects - Traykov_1999_Eur.J.Neurol_6_273 |
| Author(s) : Traykov L , Tavitian B , Jobert A , Boller F , Forette F , Crouzel C , Di Giamberardino L , Pappata S |
| Ref : Eur Journal of Neurology , 6 :273 , 1999 |
| Abstract : Traykov_1999_Eur.J.Neurol_6_273 |
| ESTHER : Traykov_1999_Eur.J.Neurol_6_273 |
| PubMedSearch : Traykov_1999_Eur.J.Neurol_6_273 |
| PubMedID: 10210906 |
| Title : Positron emission tomography study of [11C]methyl-tetrahydroaminoacridine (methyl-tacrine) in baboon brain - Tavitian_1993_Eur.J.Pharmacol_236_229 |
| Author(s) : Tavitian B , Pappata S , Bonnot-Lours S , Prenant C , Jobert A , Crouzel C , Di Giamberardino L |
| Ref : European Journal of Pharmacology , 236 :229 , 1993 |
| Abstract : Tavitian_1993_Eur.J.Pharmacol_236_229 |
| ESTHER : Tavitian_1993_Eur.J.Pharmacol_236_229 |
| PubMedSearch : Tavitian_1993_Eur.J.Pharmacol_236_229 |
| PubMedID: 8319751 |