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Inhibitor Report for: 4-aminocyclohexylalanine-derivative-25

alpha amino acid inhibitor


General
Type Pyrrolidine
Chemical_Nomenclature N-[4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]-N-methylacetamide
Canonical SMILES CC(C1CCC(CC1)N(C)C(=O)C)C(C(=O)N2CCC(C2)F)N
InChI InChI=1S/C17H30FN3O2/c1-11(16(19)17(23)21-9-8-14(18)10-21)13-4-6-15(7-5-13)20(3)12(2)22/h11,13-16H,4-10,19H2,1-3H3/t11-,13?,14-,15?,16-/m0/s1
InChIKey BZFQBRSDORUYAB-IZMWZWCESA-N
Other name(s) 277 ; N-(Trans-4-{(1s,2s)-2-Amino-3-[(3s)-3-Fluoropyrrolidin-1-Yl]-1-Methyl-3-Oxopropyl}cyclohexyl)-N-Methylacetamide ; CHEMBL1182555 ; CHEMBL1229855 ; SCHEMBL13412200 ; BDBM17323 ; DB06939
________________________________________________________________________________________________
MW|327.44
Formula|C17H30FN3O2
CAS_number|
PubChem|16122596
UniChem|BZFQBRSDORUYAB-IZMWZWCESA-N
IUPHAR|
Wikipedia|

Target
Families | 4-aminocyclohexylalanine-derivative-25 ligand of proteins in family: DPP4N_Peptidase_S9
Stucture | 1 structure: 2OPH: Human dipeptidyl peptidase IV in complex with an alpha amino acid inhibitor
Protein | human-DPP4

References:
Search PubMed for references concerning: 4-aminocyclohexylalanine-derivative-25
    Title: 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV
    Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB and Weber AE <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 17:2879, 2007 : PubMed