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Inhibitor Report for: 4-piperidino-piperidine

leaving group of hydrolysis of the inhibitor Irinotecan (CPT-11) in mammalian carboxylesterase


General
Type Leaving group, Derivative of Irinotecan, Piperidine
Chemical_Nomenclature 1-piperidin-4-ylpiperidine
Canonical SMILES C1CCN(CC1)C2CCNCC2
InChI InChI=1S/C10H20N2/c1-2-8-12(9-3-1)10-4-6-11-7-5-10/h10-11H,1-9H2
InChIKey QDVBKXJMLILLLB-UHFFFAOYSA-N
Other name(s) 4PN ; CHEBI:40117 ; CHEMBL174391 ; 4-Piperidinopiperidine ; 4-Piperidino-piperidine ; 1,4'-Bipiperidine ; 1,4'-Bipiperidyl
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MW|168.28
Formula|C10H20N2
CAS_number|4897-50-1
PubChem|78607
UniChem|QDVBKXJMLILLLB-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | 4-piperidino-piperidine ligand of proteins in family: Carb_B_Chordata
Stucture | 1 structure: 1K4Y: Crystal Structure of Rabbit Liver Carboxylesterase in Complex with 4-piperidino-piperidine (leaving group of the hydrolysis of CPT11 to SN-38)
Protein | rabit-1cxes

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