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Inhibitor Report for: 7BP-5LZ8

General
Type Pyrrolidine, Oxidanylidene, Cyanide
Chemical_Nomenclature 5-[2-[(4S)-4-tert-butyl-2-oxopyrrolidin-1-yl]ethoxy]-2-fluorobenzonitrile
Canonical SMILES CC(C)(C)C1CC(=O)N(C1)CCOC2=CC(=C(C=C2)F)C#N
InChI InChI=1S/C17H21FN2O2/c1-17(2,3)13-9-16(21)20(11-13)6-7-22-14-4-5-15(18)12(8-14)10-19/h4-5,8,13H,6-7,9,11H2,1-3H3/t13-/m1/s1
InChIKey ZXBQUZQFTWNQON-CYBMUJFWSA-N
Other name(s) 5-[2-[(4~{s})-4-~{tert}-Butyl-2-Oxidanylidene-Pyrrolidin-1-Yl]ethoxy]-2-Fluoranyl-Benzenecarbonitrile ; 7BP
________________________________________________________________________________________________
MW|304.36
Formula|C17H21FN2O2
CAS_number|
PubChem|122707119
UniChem|ZXBQUZQFTWNQON-CYBMUJFWSA-N
IUPHAR|
Wikipedia|

Target
Families | 7BP-5LZ8 ligand of proteins in family: PAF-Acetylhydrolase
Stucture | 1 structure: 5LZ8: Fragment-based inhibitors of Lipoprotein associated Phospholipase A2
Protein | human-PLA2G7

References:
Search PubMed for references concerning: 7BP-5LZ8
    Title: Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
    Woolford AJ, Day PJ, Beneton V, Berdini V, Coyle JE, Dudit Y, Grondin P, Huet P, Lee LY and Zhang X <11 more author(s)>
    Ref: Journal of Medicinal Chemistry, 59:10738, 2016 : PubMed