ARUK3004552
not specific of Notum. Studied for inhibition of protein-protein interactions targeting hypoxia-inducible factor-1 for cancer therapy
General
Type : Fragment inhibitor of Notum,Indole
Chemical_Nomenclature : 1-(2,3-dihydroindol-1-yl)prop-2-en-1-one
Canonical SMILES : C=CC(=O)N1CCC2=CC=CC=C21
InChI : InChI=1S\/C11H11NO\/c1-2-11(13)12-8-7-9-5-3-4-6-10(9)12\/h2-6H,1,7-8H2
InChIKey : MBODXUXQQPORNR-UHFFFAOYSA-N
Other name(s) : RJ0,1-(2,3-dihydro-1H-indol-1-yl)prop-2-en-1-one,CHEMBL4570581,SCHEMBL10899996,ZINC36334122
MW : 173.21
Formula : C11H11NO
CAS_number : 104902-94-5
PubChem : 23317889
UniChem : MBODXUXQQPORNR-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : ARUK3004552 ligand of proteins in family: Pectinacetylesterase-Notum
Stucture : 8BTH Structure of the human Wnt deacylase Notum in complex with ARUK3004552
Protein : human-NOTUM
References
No reference