ArM-dirhodium-cofactor
The incorporation of a synthetic, catalytically competent metallo cofactor into a protein scaffold to generate an artificial metalloenzyme (ArM) lead to new activities specific of the cofactor
General
Type : Pincer-Metal-cofactor
Chemical_Nomenclature :
Canonical SMILES :
InChI :
InChIKey :
Other name(s) :
MW : 792.44
Formula : C31H38O11Rh2
CAS_number :
PubChem :
UniChem :
IUPHAR :
Wikipedia :
Target
Families : ArM-dirhodium-cofactor ligand of proteins in family: S9N_PPCE_Peptidase_S9
Stucture :
Protein : pyrfu-Q51714
References (2)
| Title : Evolving artificial metalloenzymes via random mutagenesis - Yang_2018_Nat.Chem_10_318 |
| Author(s) : Yang H , Swartz AM , Park HJ , Srivastava P , Ellis-Guardiola K , Upp DM , Lee G , Belsare K , Gu Y , Zhang C , Moellering RE , Lewis JC |
| Ref : Nat Chem , 10 :318 , 2018 |
| Abstract : Yang_2018_Nat.Chem_10_318 |
| ESTHER : Yang_2018_Nat.Chem_10_318 |
| PubMedSearch : Yang_2018_Nat.Chem_10_318 |
| PubMedID: 29461523 |
| Title : Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation - Srivastava_2015_Nat.Commun_6_7789 |
| Author(s) : Srivastava P , Yang H , Ellis-Guardiola K , Lewis JC |
| Ref : Nat Commun , 6 :7789 , 2015 |
| Abstract : Srivastava_2015_Nat.Commun_6_7789 |
| ESTHER : Srivastava_2015_Nat.Commun_6_7789 |
| PubMedSearch : Srivastava_2015_Nat.Commun_6_7789 |
| PubMedID: 26206238 |
| Gene_locus related to this paper: pyrfu-Q51714 |