B4-4NHP
Inhibition by Butyl 4-nitrophenyl hexylphosphonate gives the adduct Butoxyhexylphosphonate on the active serine
General
Type : Organophosphate,pNP
Chemical_Nomenclature : 1-[butoxy(hexyl)phosphoryl]oxy-4-nitrobenzene
Canonical SMILES : CCCCCCP(=O)(OCCCC)OC1=CC=C(C=C1)[N+](=O)[O-]
InChI : InChI=1S\/C16H26NO5P\/c1-3-5-7-8-14-23(20,21-13-6-4-2)22-16-11-9-15(10-12-16)17(18)19\/h9-12H,3-8,13-14H2,1-2H3
InChIKey : DNVDUMRDCABCRP-UHFFFAOYSA-N
Other name(s) : BIB6300,Butyl 4-nitrophenyl hexylphosphonate,H7N,butoxy(hexyl)phosphinic acid
MW : 343.35
Formula : C16H26NO5P
CAS_number :
PubChem : 122360862
UniChem : DNVDUMRDCABCRP-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : B4-4NHP ligand of proteins in family: Hormone-sensitive_lipase_like
Stucture :
Protein : 9bact-LAE6
References (2)
| Title : Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment - Giunta_2020_ACS.Nano__ |
| Author(s) : Giunta CI , Cea-Rama I , Alonso S , Briand ML , Bargiela R , Coscolin C , Corvini PF , Ferrer M , Sanz-Aparicio J , Shahgaldian P |
| Ref : ACS Nano , : , 2020 |
| Abstract : Giunta_2020_ACS.Nano__ |
| ESTHER : Giunta_2020_ACS.Nano__ |
| PubMedSearch : Giunta_2020_ACS.Nano__ |
| PubMedID: 33306346 |
| Gene_locus related to this paper: 9zzzz-a0a2k8jn75 |
| Title : Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis - Alonso_2020_Nat.Catal_3_319 |
| Author(s) : Alonso S , Santiago G , Cea-Rama I , Fernandez-Lopez L , Coscolin C , Modregger J , Ressmann A , Martinez-Martinez M , Marrero H , Bargiela R , Pita M , Gonzalez-Alfonso JL , Briand M , Rojo D , Barbas C , Plou FJ , Golyshin PN , Shahgaldian P , Sanz-Aparicio J , Guallar V , Ferrer M |
| Ref : Nature Catalysis , 3 :319 , 2019 |
| Abstract : Alonso_2020_Nat.Catal_3_319 |
| ESTHER : Alonso_2020_Nat.Catal_3_319 |
| PubMedSearch : Alonso_2020_Nat.Catal_3_319 |
| PubMedID: |
| Gene_locus related to this paper: 9bact-LAE6 |