Benzimidazole-derivative-2
General
Type : Cyanide,Imidazole,Benzimidazole
Chemical_Nomenclature : 7-(aminomethyl)-6-(2-chlorophenyl)-1-methylbenzimidazole-5-carbonitrile
Canonical SMILES : CN1C=NC2=C1C(=C(C(=C2)C#N)C3=CC=CC=C3Cl)CN
InChI : InChI=1S\/C16H13ClN4\/c1-21-9-20-14-6-10(7-18)15(12(8-19)16(14)21)11-4-2-3-5-13(11)17\/h2-6,9H,8,19H2,1H3
InChIKey : YJLVMTVZVJSNHG-UHFFFAOYSA-N
Other name(s) : CHEMBL272114,7-(Aminomethyl)-6-(2-Chlorophenyl)-1-Methyl-1h-Benzimidazole-5-Carbonitrile,7AC,SCHEMBL3135076
MW : 296.75
Formula : C16H13ClN4
CAS_number :
PubChem : 11572962
UniChem : YJLVMTVZVJSNHG-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Benzimidazole-derivative-2 ligand of proteins in family: DPP4N_Peptidase_S9
Stucture : 3CCC Crystal Structure of Human DPP4 in complex with a benzimidazole derivative 2
Protein : human-DPP4
References (1)
| Title : Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitors - Wallace_2008_Bioorg.Med.Chem.Lett_18_2362 |
| Author(s) : Wallace MB , Feng J , Zhang Z , Skene RJ , Shi L , Caster CL , Kassel DB , Xu R , Gwaltney SL, 2nd |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :2362 , 2008 |
| Abstract : Wallace_2008_Bioorg.Med.Chem.Lett_18_2362 |
| ESTHER : Wallace_2008_Bioorg.Med.Chem.Lett_18_2362 |
| PubMedSearch : Wallace_2008_Bioorg.Med.Chem.Lett_18_2362 |
| PubMedID: 18346892 |
| Gene_locus related to this paper: human-DPP4 |