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Inhibitor Report for: C12-myristoyl-MAG-like-phosphonate

mimics the Monoacylglycerol MAG of identical size (here the 1-myristoylglycerol Monomyristin (C14:0)). The adduct on the active serine lacks the leaving group 4-nitrophenol


General
Type Organophosphate, pNP, Analogue of substrate, Lipase inhibitor, Azido
Chemical_Nomenclature 3-[dodecoxy(hydroxy)phosphoryl]propylimino-iminoazanium
Canonical SMILES CCCCCCCCCCCCOP(=O)(CCCN=[N+]=N)O
InChI InChI=1S/C15H32N3O3P/c1-2-3-4-5-6-7-8-9-10-11-14-21-22(19,20)15-12-13-17-18-16/h16H,2-15H2,1H3/p+1
InChIKey BEUWZXAEJRVUSA-UHFFFAOYSA-O
Other name(s) dodecyl 4-nitrophenyl (3-azidopropyl)phosphonate ; Dodecyl Hydrogen (S)-(3-Azidopropyl)phosphonate ; 1QX
________________________________________________________________________________________________
MW|334.42
Formula|C15H33N3O3P+
CAS_number|
PubChem|71710907
UniChem|BEUWZXAEJRVUSA-UHFFFAOYSA-O
IUPHAR|
Wikipedia|

Target
Families | C12-myristoyl-MAG-like-phosphonate ligand of proteins in family: CarbLipBact_2
Stucture | 1 structure: 4KE7: Crystal structure of monoacylglycerol lipase from Bacillus sp. H257 in complex with an 1-myristoyl glycerol analogue
Protein | bac25-mglp

References:
Search PubMed for references concerning: C12-myristoyl-MAG-like-phosphonate
    Title: Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase
    Rengachari S, Aschauer P, Schittmayer M, Mayer N, Gruber K, Breinbauer R, Birner-Gruenberger R, Dreveny I, Oberer M
    Ref: Journal of Biological Chemistry, 288:31093, 2013 : PubMed