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Inhibitor Report for: CHEMBL1234565

General
Type Pyridine, Nicotinamide, Carboxamide, Pyrazole
Chemical_Nomenclature N-[4-(5-ethyl-3-pyridin-3-ylpyrazol-1-yl)phenyl]pyridine-3-carboxamide
Canonical SMILES CCC1=CC(=NN1C2=CC=C(C=C2)NC(=O)C3=CN=CC=C3)C4=CN=CC=C4
InChI InChI=1S/C22H19N5O/c1-2-19-13-21(16-5-3-11-23-14-16)26-27(19)20-9-7-18(8-10-20)25-22(28)17-6-4-12-24-15-17/h3-15H,2H2,1H3,(H,25,28)
InChIKey CCAFHMPMIJBDRP-UHFFFAOYSA-N
Other name(s) MZL ; CHEMBL1234565 ; 3otq ; SCHEMBL3833306 ; BDBM50330097 ; N-(4-(5-ethyl-3-(pyridin-3-yl)-1H-pyrazol-1-yl)phenyl)nicotinamide
________________________________________________________________________________________________
MW|369.42
Formula|C22H19N5O
CAS_number|
PubChem|9820664
UniChem|CCAFHMPMIJBDRP-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | CHEMBL1234565 ligand of proteins in family: Epoxide_hydrolase
Stucture | 1 structure: 3OTQ: Soluble Epoxide Hydrolase in complex with pyrazole antagonist
Protein | human-EPHX2

References:
Search PubMed for references concerning: CHEMBL1234565
    Title: Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain
    Lo HY, Man CC, Fleck RW, Farrow NA, Ingraham RH, Kukulka A, Proudfoot JR, Betageri R, Kirrane T and Lombaert SD <4 more author(s)>
    Ref: Bioorganic & Medicinal Chemistry Lett, 20:6379, 2010 : PubMed