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Inhibitor Report for: CHEMBL3908555

General
Type
Chemical_Nomenclature 3-[2-(4-fluorophenoxy)ethyl]-1,3-diazaspiro[4.5]decane-2,4-dione
Canonical SMILES C1CCC2(CC1)C(=O)N(C(=O)N2)CCOC3=CC=C(C=C3)F
InChI InChI=1S/C16H19FN2O3/c17-12-4-6-13(7-5-12)22-11-10-19-14(20)16(18-15(19)21)8-2-1-3-9-16/h4-7H,1-3,8-11H2,(H,18,21)
InChIKey WWRSQXLLQVERHE-UHFFFAOYSA-N
Other name(s) 3-[2-(4-Fluoranylphenoxy)ethyl]-1,3-Diazaspiro[4.5]decane-2,4-Dione ; BDBM50197679 ; 7BJ
________________________________________________________________________________________________
MW|306.33
Formula|C16H19FN2O3
CAS_number|
PubChem|4811752
UniChem|WWRSQXLLQVERHE-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | CHEMBL3908555 ligand of proteins in family: PAF-Acetylhydrolase
Stucture | 1 structure: 5LYY: Fragment-based inhibitors of Lipoprotein associated Phospholipase A2 CHEMBL3908555
Protein | human-PLA2G7

References:
Search PubMed for references concerning: CHEMBL3908555
    Title: Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
    Woolford AJ, Day PJ, Beneton V, Berdini V, Coyle JE, Dudit Y, Grondin P, Huet P, Lee LY and Zhang X <11 more author(s)>
    Ref: Journal of Medicinal Chemistry, 59:10738, 2016 : PubMed