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Inhibitor Report for: CHEMBL3975283

General
Type Pyrrolidine, Oxidanylidene, Cyanide
Chemical_Nomenclature 5-[2-(4,4-dimethyl-2-oxopyrrolidin-1-yl)ethoxy]-2-fluorobenzonitrile
Canonical SMILES CC1(CC(=O)N(C1)CCOC2=CC(=C(C=C2)F)C#N)C
InChI InChI=1S/C15H17FN2O2/c1-15(2)8-14(19)18(10-15)5-6-20-12-3-4-13(16)11(7-12)9-17/h3-4,7H,5-6,8,10H2,1-2H3
InChIKey GRUADGBFIDAGDY-UHFFFAOYSA-N
Other name(s) 5-[2-(4,4-Dimethyl-2-Oxidanylidene-Pyrrolidin-1-Yl)ethoxy]-2-Fluoranyl-Benzenecarbonitrile ; BDBM50197659 ; 7BW
________________________________________________________________________________________________
MW|276.31
Formula|C15H17FN2O2
CAS_number|
PubChem|122707116
UniChem|GRUADGBFIDAGDY-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | CHEMBL3975283 ligand of proteins in family: PAF-Acetylhydrolase
Stucture | 1 structure: 5LZ4: Fragment-based inhibitors of Lipoprotein associated Phospholipase A2 CHEMBL3975283
Protein | human-PLA2G7

References:
Search PubMed for references concerning: CHEMBL3975283
    Title: Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
    Woolford AJ, Day PJ, Beneton V, Berdini V, Coyle JE, Dudit Y, Grondin P, Huet P, Lee LY and Zhang X <11 more author(s)>
    Ref: Journal of Medicinal Chemistry, 59:10738, 2016 : PubMed