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Inhibitor Report for: CHEMBL4075815


General
Type: Sulfur Compound, Cyanide, Naphthalen
Chemical_Nomenclature: N-[4-[(3-cyano-4-naphthalen-2-yloxyphenyl)sulfamoyl]phenyl]acetamide
Canonical SMILES: CC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=CC(=C(C=C2)OC3=CC4=CC=CC=C4C=C3)C#N
InChI: InChI=1S/C25H19N3O4S/c1-17(29)27-21-7-11-24(12-8-21)33(30,31)28-22-9-13-25(20(14-22)16-26)32-23-10-6-18-4-2-3-5-19(18)15-23/h2-15,28H,1H3,(H,27,29)
InChIKey: XLRISFAORWYVBT-UHFFFAOYSA-N
Other name(s): 8U6
MW: 457.5
Formula: C25H19N3O4S
CAS_number:
PubChem: 134693749
IUPHAR:
Wikipedia:

Target families
CHEMBL4075815 ligand of proteins in family: PAF-Acetylhydrolase

Stucture of targets
1 structure:
5YE9: The crystal structure of Lp-PLA2 in complex with a novel inhibitor

Protein target
Enzyme: human-PLA2G7

References
Search PubMed for references concerning: CHEMBL4075815
    Title: Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2
    Liu Q, Huang F, Yuan X, Wang K, Zou Y, Shen J, Xu Y
    Ref: Journal of Medicinal Chemistry, 60:10231, 2017 : PubMed