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Inhibitor Report for: CHEMBL4076637


General
Type: Sulfur Compound, Sulfonamide
Chemical_Nomenclature: N-(3,4-difluorophenyl)methanesulfonamide
Canonical SMILES: CS(=O)(=O)NC1=CC(=C(C=C1)F)F
InChI: InChI=1S/C7H7F2NO2S/c1-13(11,12)10-5-2-3-6(8)7(9)4-5/h2-4,10H,1H3
InChIKey: CRLGPRNTBCRIBM-UHFFFAOYSA-N
Other name(s): 8U3 ; BAS 00627833 ; AC1LDLO4 ; ZINC29686
MW: 207.2
Formula: C7H7F2NO2S
CAS_number: 330468-72-9
PubChem: 669158
IUPHAR:
Wikipedia:

Target families
CHEMBL4076637 ligand of proteins in family: PAF-Acetylhydrolase

Stucture of targets
1 structure:
5YE8: The crystal structure of Lp-PLA2 in complex with a novel inhibitor

Protein target
Enzyme: human-PLA2G7

References
Search PubMed for references concerning: CHEMBL4076637
    Title: Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2
    Liu Q, Huang F, Yuan X, Wang K, Zou Y, Shen J, Xu Y
    Ref: Journal of Medicinal Chemistry, 60:10231, 2017 : PubMed