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Inhibitor Report for: DSF

organosulfur cannabinoid CB1 receptor ligand. NTE Neuropathy target esterase and general LYsophospholipase_carboxylesterase or lipase inhibitor


General
Type Sulfur Compound, Sulfonyl, NTE inhibitor, Not A/B H target, Lipase inhibitor
Chemical_Nomenclature dodecane-1-sulfonyl fluoride
Canonical SMILES CCCCCCCCCCCCS(=O)(=O)F
InChI InChI=1S/C12H25FO2S/c1-2-3-4-5-6-7-8-9-10-11-12-16(13,14)15/h2-12H2,1H3
InChIKey UVLRFDMRDPQRSM-UHFFFAOYSA-N
Other name(s) CHEMBL97038 ; Dodecanesulfonyl fluoride ; SCHEMBL1470419 ; DNC014029 ; LS-191509
________________________________________________________________________________________________
MW|252.38
Formula|C12H25FO2S
CAS_number|
PubChem|18516661
UniChem|UVLRFDMRDPQRSM-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | DSF ligand of proteins in family: LYsophospholipase_carboxylesterase, Acidic_Lipase

References:
Search PubMed for references concerning: DSF
    Title: Lysophospholipase inhibition by organophosphorus toxicants
    Quistad GB, Casida JE
    Ref: Toxicol Appl Pharmacol, 196:319, 2004 : PubMed

            

    Title: Novel trifluoromethyl ketones as potent gastric lipase inhibitors
    Kokotos G, Kotsovolou S, Verger R
    Ref: Chembiochem, 4:90, 2003 : PubMed

            

    Title: Toxicological and structural features of organophosphorus and organosulfur cannabinoid CB1 receptor ligands
    Segall Y, Quistad GB, Sparks SE, Nomura DK, Casida JE
    Ref: Toxicol Sci, 76:131, 2003 : PubMed