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Inhibitor Report for: Dibutyl-dichlorovinyl-phosphate~DBVP

potent organophosphorus neuropathy target esterase (NTE not alpha/beta hydrolase) inhibitor


General
Type Organophosphate, NTE inhibitor, Not A/B H target
Chemical_Nomenclature 1-(butoxy-(2,2-dichloroethenoxy)phosphoryl)oxybutane
Canonical SMILES CCCCOP(=O)(OCCCC)OC(=CCl)Cl
InChI InChI=1S/C10H19Cl2O4P/c1-3-5-7-14-17(13,15-8-6-4-2)16-10(12)9-11/h9H,3-8H2,1-2H3
InChIKey ZRSXWECQLMXKHF-UHFFFAOYSA-N
Other name(s) DBDCVP ; DBVP ; di-n-butyl dichlorvos ; 2,2-dichlorovinyldibutylphosphate ; Dibutyl 2,2-dichlorovinyl phosphate ; EINECS 242-584-1 ; BRN 1712889 ; Di-n-butyl-2,2-dichlorovinyl phosphate [MeSH: di-n-butyl-2,2-dichlorovinyl phosphate] ; AI3-20756 ; Phosphoric acid, dibutyl 2,2-dichlorovinyl ester ; 4-01-00-02064 ; Phosphoric acid, dibutyl 2,2-dichloroethenyl ester ; 18795-58-9
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MW|305.13
Formula|C10H19Cl2O4P
CAS_number|
PubChem|54562823
UniChem|ZRSXWECQLMXKHF-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: Dibutyl-dichlorovinyl-phosphate~DBVP

6 more
    Title: Effects of S-ethyl hexahydro-1H-azepine-1-carbothioate (molinate) on di-n-butyl dichlorovinyl phosphate (DBDCVP) neuropathy
    Moretto A, Gardiman G, Panfilo S, Colle MA, Lock EA, Lotti M
    Ref: Toxicol Sci, 62:274, 2001 : PubMed

            

    Title: Brainstem axolemmal protein phosphorylation in vitro in hens dosed with di-1-butyl-2,2-dichlorovinyl phosphate
    Huggins DJ, Richardson RJ
    Ref: J Toxicol Environ Health A, 56:263, 1999 : PubMed

            

    Title: Inhibition of carboxylesterases in SH-SY5Y human and NB41A3 mouse neuroblastoma cells by organophosphorus esters
    Ehrich M, Correll L
    Ref: J Toxicol Environ Health, 53:385, 1998 : PubMed