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Inhibitor Report for: EPN-oxon

EPN (Oxygen replaces the sulfur atom of EPN)


General
Type Insecticide, Organophosphate, pNP
Chemical_Nomenclature phenylphosphoric acid O-ethyl O-p-nitrophenyl ester
Canonical SMILES CCOP(=O)(C1=CC=CC=C1)OC2=CC=C(C=C2)[N+](=O)[O-]
InChI InChI=1S/C14H14NO5P/c1-2-19-21(18,14-6-4-3-5-7-14)20-13-10-8-12(9-11-13)15(16)17/h3-11H,2H2,1H3
InChIKey PDABPGQGULTJFY-UHFFFAOYSA-N
Other name(s) EPN oxon ; CCRIS 7776 ; BRN 2949526
________________________________________________________________________________________________
MW|307.24
Formula|C14H14NO5P
CAS_number|2012-00-2
PubChem|107973
UniChem|PDABPGQGULTJFY-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | EPN-oxon ligand of proteins in family: ACHE

References:
Search PubMed for references concerning: EPN-oxon
    Title: Degradation by rat tissues in vitro of organophosphorus esters which inhibit cholinesterase
    Pla A, Johnson MK
    Ref: Biochemical Pharmacology, 38:1527, 1989 : PubMed

            

    Title: Enhancement of the binding of O-ethyl O-p-nitrophenyl phenylphosphonate (EPNoxon) to microsomal carboxylesterase by NAD in vitro
    Sugiyama S, Hosokawa M, Igarashi T, Ueno K, Satoh T, Kitagawa H
    Ref: Japanese Journal of Pharmacology, 37:39, 1985 : PubMed