Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: Evodiamine

General
Type Derivative of Evodiamine, Natural, beta-carboline, Not A/B H target, Multitarget
Chemical_Nomenclature (1S)-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
Canonical SMILES CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
InChI InChI=1S/C19H17N3O/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22/h2-9,18,20H,10-11H2,1H3/t18-/m0/s1
InChIKey TXDUTHBFYKGSAH-SFHVURJKSA-N
Other name(s) d-Evodiamine ; (+)-Evodiamine ; UNII-C01825BVNL ; CHEBI:4948 ; CHEMBL463165 ; DTXSID10966123 ; ZINC898159
________________________________________________________________________________________________
MW|303.4
Formula|C19H17N3O
CAS_number|518-17-2
PubChem|442088
UniChem|TXDUTHBFYKGSAH-SFHVURJKSA-N
IUPHAR|
Wikipedia|

Target

References:
Search PubMed for references concerning: Evodiamine

3 more
    Title: Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine
    Huang G, Kling B, Darras FH, Heilmann J, Decker M
    Ref: Eur Journal of Medicinal Chemistry, 81C:15, 2014 : PubMed

            

    Title: Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine
    Decker M
    Ref: Eur Journal of Medicinal Chemistry, 40:305, 2005 : PubMed

            

    Title: Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa
    Park CH, Kim SH, Choi W, Lee YJ, Kim JS, Kang SS, Suh YH
    Ref: Planta Med, 62:405, 1996 : PubMed