FP-TAMRA
Tetramethylrhodamine fluorophosphonate. Serine Hydrolase probe consisting of a tag linked to a fluorophosphonate (FP) group, which specifically and covalently labels serines of enzymatically active serine hydrolases. ABPP-Probe (activity based protein profiling probe)
General
Type : Organophosphate,ABPP-Probe,Benzoate,Xanthene
Chemical_Nomenclature : 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-[10-[ethoxy(fluoro)phosphoryl]decylcarbamoyl]benzoate
Canonical SMILES : CCOP(=O)(CCCCCCCCCCNC(=O)C1=CC(=C(C=C1)C2=C3C=CC(=[N+](C)C)C=C3OC4=C2C=CC(=C4)N(C)C)C(=O)[O-])F
InChI : InChI=1S\/C37H47FN3O6P\/c1-6-46-48(38,45)22-14-12-10-8-7-9-11-13-21-39-36(42)26-15-18-29(32(23-26)37(43)44)35-30-19-16-27(40(2)3)24-33(30)47-34-25-28(41(4)5)17-20-31(34)35\/h15-20,23-25H,6-14,21-22H2,1-5H3,(H-,39,42,43,44)
InChIKey : JEVJWIYMEMUCFU-UHFFFAOYSA-N
Other name(s) : TAMRA-FP
MW : 679,76
Formula : C37H47FN3O6P
CAS_number :
PubChem : 139035304
UniChem : JEVJWIYMEMUCFU-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families :
Stucture :
Protein :
References (2)
| Title : Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases - Baggelaar_2017_ACS.Chem.Biol_12_852 |
| Author(s) : Baggelaar MP , van Esbroeck AC , van Rooden EJ , Florea BI , Overkleeft HS , Marsicano G , Chaouloff F , van der Stelt M |
| Ref : ACS Chemical Biology , 12 :852 , 2017 |
| Abstract : Baggelaar_2017_ACS.Chem.Biol_12_852 |
| ESTHER : Baggelaar_2017_ACS.Chem.Biol_12_852 |
| PubMedSearch : Baggelaar_2017_ACS.Chem.Biol_12_852 |
| PubMedID: 28106377 |
| Gene_locus related to this paper: human-ABHD4 , human-ABHD6 , human-ABHD12 , human-DAGLA , human-MGLL |
| Title : Biochemical and pharmacological characterization of human alpha\/beta-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12) - Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| Author(s) : Navia-Paldanius D , Savinainen JR , Laitinen JT |
| Ref : J Lipid Res , 53 :2413 , 2012 |
| Abstract : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| ESTHER : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| PubMedSearch : Navia-Paldanius_2012_J.Lipid.Res_53_2413 |
| PubMedID: 22969151 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 |