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Inhibitor Report for: GTPL9797


General
Type: Trifluoro, Piperidine, Sulfur Compound, Sulfonamide
Chemical_Nomenclature: 4-amino-N-[4-[4-chloro-3-(trifluoromethyl)phenoxy]-3-cyanophenyl]benzenesulfonamide
Canonical SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=CC(=C(C=C2)OC3=CC(=C(C=C3)Cl)C(F)(F)F)C#N
InChI: InChI=1S/C20H13ClF3N3O3S/c21-18-7-4-15(10-17(18)20(22,23)24)30-19-8-3-14(9-12(19)11-25)27-31(28,29)16-5-1-13(26)2-6-16/h1-10,27H,26H2
InChIKey: GADGQEKPNKSGMT-UHFFFAOYSA-N
Other name(s): Compound 37 ; GTPL9797 ; Lp-PLA2-IN-3 ; CHEMBL4088985
MW: 467.84
Formula: C20H13ClF3N3O3S
CAS_number:
PubChem: 132427687
IUPHAR: 9797
Wikipedia:

Target families
GTPL9797 ligand of proteins in family: PAF-Acetylhydrolase
No structure

Protein target
Enzyme: human-PLA2G7

References
Search PubMed for references concerning: GTPL9797
    Title: Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2
    Liu Q, Huang F, Yuan X, Wang K, Zou Y, Shen J, Xu Y
    Ref: Journal of Medicinal Chemistry, 60:10231, 2017 : PubMed