GVB
General
Type : Piperidine
Chemical_Nomenclature : (3R,4S)-1-(3,4-dimethoxyphenyl)-3-(3-methylphenyl)piperidin-4-amine
Canonical SMILES : CC1=CC=CC(=C1)C2CN(CCC2N)C3=CC(=C(C=C3)OC)OC
InChI : InChI=1S\/C20H26N2O2\/c1-14-5-4-6-15(11-14)17-13-22(10-9-18(17)21)16-7-8-19(23-2)20(12-16)24-3\/h4-8,11-12,17-18H,9-10,13,21H2,1-3H3\/t17-,18-\/m0\/s1
InChIKey : DQJXBZGPJVSWFI-ROUUACIJSA-N
Other name(s) : DB07851
MW : 326.44
Formula : C20H26N2O2
CAS_number :
PubChem : 24798721
UniChem : DQJXBZGPJVSWFI-ROUUACIJSA-N
IUPHAR :
Wikipedia :
Target
Families : GVB ligand of proteins in family: DPP4N_Peptidase_S9
Stucture : 2JID Human Dipeptidyl peptidase IV in complex with 1-(3,4-Dimethoxy-phenyl) -3-m-tolyl-piperidine-4-ylamine
Protein : human-DPP4
References (1)
| Title : 1,3-disubstituted 4-aminopiperidines as useful tools in the optimization of the 2-aminobenzo[a]quinolizine dipeptidyl peptidase IV inhibitors - Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| Author(s) : Lubbers T , Bohringer M , Gobbi L , Hennig M , Hunziker D , Kuhn B , Loffler B , Mattei P , Narquizian R , Peters JU , Ruff Y , Wessel HP , Wyss P |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :2966 , 2007 |
| Abstract : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| ESTHER : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| PubMedSearch : Lubbers_2007_Bioorg.Med.Chem.Lett_17_2966 |
| PubMedID: 17418568 |
| Gene_locus related to this paper: human-DPP4 |