Geranylphenazinediol

Geranylphenazinediol from Streptomyces sp. strain LB173. This strain was isolated from ambient sediment of a Saccharina latissima specimen growing in the Kiel Fjord.IC50 geranylphenazinediol 2.62+/- 0.35 microM

General

Type : Natural,Phenazine

Chemical_Nomenclature : 9-[(2E)-3,7-dimethylocta-2,6-dienyl]-6-hydroxy-5H-phenazin-1-one

Canonical SMILES : C\/C(=CCc1ccc(c2c1nc1c(O)cccc1n2)O)\/CCC=C(C)C || CC(=CCCC(=CCC1=C2C(=C(C=C1)O)NC3=CC=CC(=O)C3=N2)C)C

InChI : InChI=1S\/C22H24N2O2\/c1-14(2)6-4-7-15(3)10-11-16-12-13-19(26)22-20(16)24-21-17(23-22)8-5-9-18(21)25\/h5-6,8-10,12-13,25-26H,4,7,11H2,1-3H3\/b15-10+

InChIKey : KMFWEUARPSOWSB-XNTDXEJSSA-N

Other name(s) : Geranyl-phenazine-diol,CHEMBL2071424,BDBM50390003


MW : 348.43

Formula : C22H24N2O2

CAS_number :

PubChem : 60201712

UniChem : KMFWEUARPSOWSB-XNTDXEJSSA-N

IUPHAR :

Wikipedia :

Target

Families : Geranylphenazinediol ligand of proteins in family: ACHE

Stucture :

Protein :

References (1)

Title : Geranylphenazinediol, an acetylcholinesterase inhibitor produced by a Streptomyces species - Ohlendorf_2012_J.Nat.Prod_75_1400
Author(s) : Ohlendorf B , Schulz D , Erhard A , Nagel K , Imhoff JF
Ref : Journal of Natural Products , 75 :1400 , 2012
Abstract : Ohlendorf_2012_J.Nat.Prod_75_1400
ESTHER : Ohlendorf_2012_J.Nat.Prod_75_1400
PubMedSearch : Ohlendorf_2012_J.Nat.Prod_75_1400
PubMedID: 22775474