Indolesufonamide1
General
Type : Sulfur Compound,Indole,Sulfonamide
Chemical_Nomenclature : [2-(2,4-dichlorophenyl)-1-methylsulfonylindol-3-yl]methanamine
Canonical SMILES : CS(=O)(=O)N1C2=CC=CC=C2C(=C1C3=C(C=C(C=C3)Cl)Cl)CN
InChI : InChI=1S\/C16H14Cl2N2O2S\/c1-23(21,22)20-15-5-3-2-4-11(15)13(9-19)16(20)12-7-6-10(17)8-14(12)18\/h2-8H,9,19H2,1H3
InChIKey : MTMKFBZYRGNPDF-UHFFFAOYSA-N
Other name(s) : GTPL8301,Compound 1 (Xiao et al. 2014),[2-(2,4-dichlorophenyl)-1-methylsulfonylindol-3-yl]methanamine,1-[2-(2,4-Dichlorophenyl)-1-(Methylsulfonyl)-1h-Indol-3-Yl]methanamine,CJP
MW : 369.26
Formula : C16H14Cl2N2O2S
CAS_number :
PubChem : 91623329
UniChem : MTMKFBZYRGNPDF-UHFFFAOYSA-N
IUPHAR : 8301
Wikipedia :
Target
Families : Indolesufonamide1 ligand of proteins in family: DPP4N_Peptidase_S9
Stucture : 4PV7 Cocrystal structure of dipeptidyl-peptidase 4 with an indole scaffold inhibitor
Protein : human-DPP4
References (1)
| Title : Discovery of dipeptidyl peptidase IV (DPP4) inhibitors based on a novel indole scaffold - Xiao_2014_Chin.Chem.Lett_25_673 |
| Author(s) : Xiao P , Guo R , Huang S , Cui H , Ye S , Zhang Z |
| Ref : Chin Chem Lett , 25 :673 , 2014 |
| Abstract : Xiao_2014_Chin.Chem.Lett_25_673 |
| ESTHER : Xiao_2014_Chin.Chem.Lett_25_673 |
| PubMedSearch : Xiao_2014_Chin.Chem.Lett_25_673 |
| PubMedID: |
| Gene_locus related to this paper: human-DPP4 |