Isosorbide-2-benzylcarbamate-5-benzyl-ether
General
Type : Isosorbide,Carbamate
Chemical_Nomenclature : [(3R,3aR,6S,6aR)-3-phenylmethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] N-benzylcarbamate
Canonical SMILES : C1C(C2C(O1)C(CO2)OC(=O)NCC3=CC=CC=C3)OCC4=CC=CC=C4
InChI : InChI=1S\/C21H23NO5\/c23-21(22-11-15-7-3-1-4-8-15)27-18-14-26-19-17(13-25-20(18)19)24-12-16-9-5-2-6-10-16\/h1-10,17-20H,11-14H2,(H,22,23)\/t17-,18+,19-,20-\/m1\/s1
InChIKey : ROBGGBFLUNTBTH-IYWMVGAKSA-N
Other name(s) : CHEMBL601889,BDBM50306692,2-(Benzylaminocarbonyloxy)-5-O-benzyl-1,4:3,6-dianhydro-D-glucitol,18a
MW : 369.41
Formula : C21H23NO5
CAS_number :
PubChem : 46232813
UniChem : ROBGGBFLUNTBTH-IYWMVGAKSA-N
IUPHAR :
Wikipedia :
Target
Families : Isosorbide-2-benzylcarbamate-5-benzyl-ether ligand of proteins in family: BCHE
Stucture :
Protein : human-BCHE
References (1)
| Title : Isosorbide-based cholinesterase inhibitors\; replacement of 5-ester groups leading to increased stability - Dillon_2010_Bioorg.Med.Chem_18_1045 |
| Author(s) : Dillon GP , Gaynor JM , Khan D , Carolan CG , Ryder SA , Marquez JF , Reidy S , Gilmer JF |
| Ref : Bioorganic & Medicinal Chemistry , 18 :1045 , 2010 |
| Abstract : Dillon_2010_Bioorg.Med.Chem_18_1045 |
| ESTHER : Dillon_2010_Bioorg.Med.Chem_18_1045 |
| PubMedSearch : Dillon_2010_Bioorg.Med.Chem_18_1045 |
| PubMedID: 20093035 |