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JCP-265

General

Type : Carbamate

Chemical_Nomenclature : [(2S)-1-[[3-(2-bromoethoxy)-4-chloro-1-oxoisochromen-7-yl]amino]-1-oxopropan-2-yl] N-phenylcarbamate

Canonical SMILES : CC(C(=O)NC1=CC2=C(C=C1)C(=C(OC2=O)OCCBr)Cl)OC(=O)NC3=CC=CC=C3

InChI : InChI=1S\/C21H18BrClN2O6\/c1-12(30-21(28)25-13-5-3-2-4-6-13)18(26)24-14-7-8-15-16(11-14)19(27)31-20(17(15)23)29-10-9-22\/h2-8,11-12H,9-10H2,1H3,(H,24,26)(H,25,28)\/t12-\/m0\/s1

InChIKey : VOIQWVHTMKOBBL-LBPRGKRZSA-N

Other name(s) : JCP 265,(S)-N-[3-(2-Bromoethoxy)-4-chloro-1-oxo-1H-2-benzopyran-7-yl]-2-[[(phenylamino)carbonyl]oxy]-propanamide

MW : 509.7

Formula : C21H18BrClN2O6

CAS_number : 140652-99-9

PubChem : 154724049

UniChem : VOIQWVHTMKOBBL-LBPRGKRZSA-N

IUPHAR :

Wikipedia :

Target

Families : JCP-265 ligand of proteins in family: ABHD6-Lip

Stucture :

Protein : human-ABHD6

References (1)

Title : An in vivo multiplexed small-molecule screening platform - Gruner_2016_Nat.Methods_13_883
Author(s) : Gruner BM , Schulze CJ , Yang D , Ogasawara D , Dix MM , Rogers ZN , Chuang CH , McFarland CD , Chiou SH , Brown JM , Cravatt BF , Bogyo M , Winslow MM
Ref : Nat Methods , 13 :883 , 2016
Abstract : Gruner_2016_Nat.Methods_13_883
ESTHER : Gruner_2016_Nat.Methods_13_883
PubMedSearch : Gruner_2016_Nat.Methods_13_883
PubMedID: 27617390