JZP-MA-11

General

Type : Sulfur Compound,PET probe,Thiadiazol,Piperidine,Carbamate

Chemical_Nomenclature :

Canonical SMILES : C1=C(C=CC(=C1)N(C(=O)OC2=NSN=C2N3CCCCC3)C)F

InChI : InChI=1S\/C15H17FN4O2S\/c1-19(12-7-5-11(16)6-8-12)15(21)22-14-13(17-23-18-14)20-9-3-2-4-10-20\/h5-8H,2-4,9-10H2,1H3

InChIKey : NLWSYKNCVGFXOV-UHFFFAOYSA-N

Other name(s) : [18F]JZP-MA-11


MW : 336.38

Formula : C15H17FN4O2S

CAS_number :

PubChem :

UniChem : NLWSYKNCVGFXOV-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : JZP-MA-11 ligand of proteins in family: ABHD6-Lip

Stucture :

Protein : human-ABHD6

References (1)

Title : Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid alpha\/beta-Hydrolase Domain 6 (ABHD6) - Mardon_2022_J.Med.Chem__
Author(s) : Mardon K , Patel JZ , Savinainen JR , Stimson DHR , Oyagawa CRM , Grimsey NL , Migotto MA , Njiru GFM , Hamilton BR , Cowin G , Yli-Kauhaluoma J , Vanduffel W , Blakey I , Bhalla R , Cawthorne C , Celen S , Bormans G , Thurecht KJ , Ahamed M
Ref : Journal of Medicinal Chemistry , : , 2022
Abstract : Mardon_2022_J.Med.Chem__
ESTHER : Mardon_2022_J.Med.Chem__
PubMedSearch : Mardon_2022_J.Med.Chem__
PubMedID: 36516997