KT185
General
Type : Piperidine,Triazol
Chemical_Nomenclature : [3-[4-[1-(2-phenylpiperidine-1-carbonyl)triazol-4-yl]phenyl]phenyl]-piperidin-1-ylmethanone
Canonical SMILES : C1CCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(C=C3)C4=CN(N=N4)C(=O)N5CCCCC5C6=CC=CC=C6
InChI : InChI=1S\/C32H33N5O2\/c38-31(35-19-6-2-7-20-35)28-13-9-12-27(22-28)24-15-17-25(18-16-24)29-23-37(34-33-29)32(39)36-21-8-5-14-30(36)26-10-3-1-4-11-26\/h1,3-4,9-13,15-18,22-23,30H,2,5-8,14,19-21H2
InChIKey : SGQNTNACVSWXMA-UHFFFAOYSA-N
Other name(s) : KT-185,CHEMBL3263579,(2-Phenylpiperidin-1-yl)(4-(3'-(piperidine-1-carbonyl)-[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)methanone,BDBM50010336
MW : 519.6
Formula : C32H33N5O2
CAS_number : 1472640-86-0
PubChem : 53364498
UniChem : SGQNTNACVSWXMA-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (2)
| Title : Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach - Choudhary_2020_Front.Immunol_11_1664 |
| Author(s) : Choudhary S , Malik YS , Tomar S |
| Ref : Front Immunol , 11 :1664 , 2020 |
| Abstract : Choudhary_2020_Front.Immunol_11_1664 |
| ESTHER : Choudhary_2020_Front.Immunol_11_1664 |
| PubMedSearch : Choudhary_2020_Front.Immunol_11_1664 |
| PubMedID: 32754161 |
| Title : Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha\/beta-hydrolase domain containing 6 (ABHD6) - Hsu_2013_J.Med.Chem_56_8270 |
| Author(s) : Hsu KL , Tsuboi K , Chang JW , Whitby LR , Speers AE , Pugh H , Cravatt BF |
| Ref : Journal of Medicinal Chemistry , 56 :8270 , 2013 |
| Abstract : Hsu_2013_J.Med.Chem_56_8270 |
| ESTHER : Hsu_2013_J.Med.Chem_56_8270 |
| PubMedSearch : Hsu_2013_J.Med.Chem_56_8270 |
| PubMedID: 24152295 |