Melatonin-alkylbenzylamine-Cpd5
huBuChE IC(50)=1.20 microM, huAChE IC(50) = 177.49 microM
General
Type : Antioxidant,Derivative of Tryptamine,Indole,Multitarget,Alkyl linked bis-ligand
Chemical_Nomenclature : 5-hydroxy-1-(12-((3-hydroxybenzyl)(methyl)amino)dodecyl)-1H-indole-3-carbaldehyde
Canonical SMILES : C(CCCCCCCCN(CC1=CC(=CC=C1)O)C)CCC[N]3C2=CC=C(C=C2C(=C3)C=O)O
InChI : InChI=1S\/C29H40N2O3\/c1-30(21-24-13-12-14-26(33)19-24)17-10-8-6-4-2-3-5-7-9-11-18-31-22-25(23-32)28-20-27(34)15-16-29(28)31\/h12-16,19-20,22-23,33-34H,2-11,17-18,21H2,1H3
InChIKey : FSMMMQWAIKAMQM-UHFFFAOYSA-N
Other name(s) :
MW : 465.31
Formula : C29H40N2O3
CAS_number :
PubChem :
UniChem : FSMMMQWAIKAMQM-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
References (1)
| Title : Dual functional antioxidant and butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis and evaluation of novel melatonin-alkylbenzylamine hybrids - Liu_2023_Bioorg.Med.Chem_78_117146 |
| Author(s) : Liu P , Cheng M , Guo J , Cao D , Luo J , Wan Y , Fang Y , Jin Y , Xie SS , Liu J |
| Ref : Bioorganic & Medicinal Chemistry , 78 :117146 , 2023 |
| Abstract : Liu_2023_Bioorg.Med.Chem_78_117146 |
| ESTHER : Liu_2023_Bioorg.Med.Chem_78_117146 |
| PubMedSearch : Liu_2023_Bioorg.Med.Chem_78_117146 |
| PubMedID: 36580744 |