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Inhibitor Report for: MmPPOX

General
Type Oxadiazolone, Oxadiazol, Lipase inhibitor, Phenoxyphenyl
Chemical_Nomenclature 5-methoxy-3-(3-phenoxyphenyl)-1,3,4-oxadiazol-2-one
Canonical SMILES COC1=NN(C(=O)O1)C2=CC(=CC=C2)OC3=CC=CC=C3
InChI InChI=1S/C15H12N2O4/c1-19-14-16-17(15(18)21-14)11-6-5-9-13(10-11)20-12-7-3-2-4-8-12/h2-10H,1H3
InChIKey MAWQNKAJQQKDTD-UHFFFAOYSA-N
Other name(s) SCHEMBL6551376 ; CHEMBL2171701 ; 5-Methoxy-3-(3-phenoxyphenyl)-1,3,4-oxadiazol-2(3H)-one
________________________________________________________________________________________________
MW|284
Formula|C15H13N2O5
CAS_number|
PubChem|18184779
UniChem|MAWQNKAJQQKDTD-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | MmPPOX ligand of proteins in family: Acidic_Lipase

References:
Search PubMed for references concerning: MmPPOX
    Title: MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth
    Delorme V, Diomande SV, Dedieu L, Cavalier JF, Carriere F, Kremer L, Leclaire J, Fotiadu F, Canaan S
    Ref: PLoS ONE, 7:e46493, 2012 : PubMed

            

    Title: Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones.
    Point V, Pavan Kumar KV, Marc S, Delorme V, Parsiegla G, Amara S, Carriere F, Buono G, Fotiadu F and Cavalier JF <2 more author(s)>
    Ref: Eur Journal of Medicinal Chemistry, 58:452, 2012 : PubMed

            


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