NBD-AP-MPF

General

Type : Organophosphate,ABPP-Probe,NBD-nitro-benzoxadiazol-fluorescent,Benzoxadiazole

Chemical_Nomenclature : N-[5-[fluoro(methyl)phosphoryl]oxypentyl]-4-nitro-2,1,3-benzoxadiazol-7-amine

Canonical SMILES : CP(=O)(OCCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])F

InChI : InChI=1S\/C12H16FN4O5P\/c1-23(13,20)21-8-4-2-3-7-14-9-5-6-10(17(18)19)12-11(9)15-22-16-12\/h5-6,14H,2-4,7-8H2,1H3

InChIKey : CQRZHOIPJNBZEC-UHFFFAOYSA-N

Other name(s) : Nbd-aminopentylmethylphosphonofluoridate,Phosphonofluoridic acid, methyl-, 5-((7-nitro-4-benzofurazanyl)amino)pentyl ester,AC1L2PEK,AC1Q1Z0N


MW : 346.25

Formula : C12H16FN4O5P

CAS_number : 96304-85-7

PubChem : 125903

UniChem : CQRZHOIPJNBZEC-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : NBD-AP-MPF ligand of proteins in family: ACHE

Stucture :

Protein : torca-ACHE

References (2)

Title : Conformational change at the active center of serine-proteases upon their binding to alpha 2-macroglobulin - Martini_1989_Biochimie_71_325
Author(s) : Martini JL , Pochon F
Ref : Biochimie , 71 :325 , 1989
Abstract : Martini_1989_Biochimie_71_325
ESTHER : Martini_1989_Biochimie_71_325
PubMedSearch : Martini_1989_Biochimie_71_325
PubMedID: 2472840

Title : Fluorescent phosphonate labels for serine hydrolases. Kinetic and spectroscopic properties of (7-nitrobenz-2-oxa-1,3-diazole)aminoalkyl methylphosphonofluoridates and their conjugates with acetylcholinesterase molecular forms - Berman_1985_J.Biol.Chem_260_3462
Author(s) : Berman HA , Olshefski DF , Gilbert M , Decker MM
Ref : Journal of Biological Chemistry , 260 :3462 , 1985
Abstract : Berman_1985_J.Biol.Chem_260_3462
ESTHER : Berman_1985_J.Biol.Chem_260_3462
PubMedSearch : Berman_1985_J.Biol.Chem_260_3462
PubMedID: 3972833