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Inhibitor Report for: NBD-HE-HP

ABPP-Probe labels many serine hydrolases and not only alpha/beta hydrolases . Compound XXX1 in Oskolkova_2003_Chem.Phys.Lipids_125_103


General
Type Organophosphate, ABPP-Probe, NBD-nitro-benzoxadiazol-fluorescent, pNP, Benzoxadiazole
Chemical_Nomenclature N-[2-[hexyl-(4-nitrophenoxy)phosphoryl]oxyethyl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide
Canonical SMILES CCCCCCP(=O)(OCCNC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])OC3=CC=C(C=C3)[N+](=O)[O-]
InChI InChI=1S/C26H35N6O9P/c1-2-3-4-8-19-42(38,40-21-12-10-20(11-13-21)31(34)35)39-18-17-28-24(33)9-6-5-7-16-27-22-14-15-23(32(36)37)26-25(22)29-41-30-26/h10-15,27H,2-9,16-19H2,1H3,(H,28,33)
InChIKey ZFHHVTNYROZCIO-UHFFFAOYSA-N
Other name(s) AC1LD8L8 ; SCHEMBL13199489 ; LP106166 ; 2-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexaneamido}ethyl 4-nitrophenyl hexylphosphonate ; 689264-29-7 ; N-[2-[hexyl-(4-nitrophenoxy)phosphoryl]oxyethyl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide ; (O-((6-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)aminoethyl-O-(n-hexyl)phosphonic acid p-nitrophenyl ester
________________________________________________________________________________________________
MW|606.56
Formula|C26H35N6O9P
CAS_number|
PubChem|644117
UniChem|ZFHHVTNYROZCIO-UHFFFAOYSA-N
IUPHAR|
Wikipedia|


References:
Search PubMed for references concerning: NBD-HE-HP

2 more
    Title: Functional proteomic analysis of lipases and esterases in cultured human adipocytes
    Schicher M, Morak M, Birner-Gruenberger R, Kayer H, Stojcic B, Rechberger G, Kollroser M, Hermetter A
    Ref: J Proteome Res, 9:6334, 2010 : PubMed

            

    Title: Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases
    Schmidinger H, Birner-Gruenberger R, Riesenhuber G, Saf R, Susani-Etzerodt H, Hermetter A
    Ref: Chembiochem, 6:1776, 2005 : PubMed

            

    Title: Fluorescent organophosphonates as inhibitors of microbial lipases
    Oskolkova OV, Saf R, Zenzmaier E, Hermetter A
    Ref: Chemistry & Physic of Lipids, 125:103, 2003 : PubMed