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Inhibitor Report for: Novichok-5~A-232

Novichok (newcomer/ newbie/ novice, beginner/) is a series of binary chemical weapons developed by the Soviet Union and Russia between 1971 and 1993. Mirzayanov provided the first description of these agents but are somewhat different from the structures identified later


General
Type Organophosphate, Chemical Warfare Agent, Novichok
Chemical_Nomenclature 3-chloro-2-methylpropyl ((chlorofluoromethylene)amino)oxyphosphonofluoridate
Canonical SMILES CC(CCl)OP(=O)(ON=C(F)Cl)F
InChI InChI=1S/C4H6Cl2F2NO3P/c1-3(2-5)11-13(8,10)12-9-4(6)7/h3H,2H2,1H3/b9-4-
InChIKey FOHQFVXLTJEIKH-WTKPLQERSA-N
Other name(s) A-232 ; A232 ; SCHEMBL21981151
________________________________________________________________________________________________
MW|255.97
Formula|C4H6Cl2F2NO3P
CAS_number|16415-09-1
PubChem|146586259
UniChem|FOHQFVXLTJEIKH-WTKPLQERSA-N
IUPHAR|
Wikipedia|Novichok_agent

Target
Families | Novichok-5~A-232 ligand of proteins in family: ACHE, BCHE
Protein | human-ACHE

References:
Search PubMed for references concerning: Novichok-5~A-232
    Title: Novichok agents: a historical, current, and toxicological perspective
    Chai PR, Hayes BD, Erickson TB, Boyer EW
    Ref: Toxicol Commun, 2:45, 2018 : PubMed

            

    Title: Chemical warfare agent NOVICHOK - mini-review of available data
    Nepovimova E, Kuca K
    Ref: Food & Chemical Toxicology, 121:343, 2018 : PubMed

            

    Title: Novichok: a murderous nerve agent attack in the UK
    Vale JA, Marrs TO, Maynard RC
    Ref: Clinical Toxicology (Phila), 56:1093, 2018 : PubMed