OBDPO
a metabolic precursor to an NTE inhibitor tri-o-cresyl phosphate or TOCP
General
Type : Organophosphate,NTE inhibitor,Cyclic OP,Not A\/B H target
Chemical_Nomenclature : 2-hydroxy-2-octyl-4H-1,3,2$l^{4}-benzodioxaphosphinine || 2-octyl-4H-1,3,2lambda5-benzodioxaphosphinine 2-oxide
Canonical SMILES : CCCCCCCCP1(=O)OCC2=CC=CC=C2O1
InChI : InChI=1S\/C15H24O3P\/c1-2-3-4-5-6-9-12-19(16)17-13-14-10-7-8-11-15(14)18-19\/h7-8,10-11,16H,2-6,9,12-13H2,1H3 || InChI=1S\/C15H23O3P\/c1-2-3-4-5-6-9-12-19(16)17-13-14-10-7-8-11-15(14)18-19\/h7-8,10-11H,2-6,9,12-13H2,1H3
InChIKey : YTURVHUJFLMJCA-UHFFFAOYSA-N
Other name(s) : 2-octyl-4H-1,3,2-benzodioxaphosphorin-2-oxide,C092561000,2-Octyl-4H-1,3,2-benzodioxaphosphorin 2-oxide,2-octyl-4H-1,3,2lambda5-benzodioxaphosphinine 2-oxide,4H-1,3,2-Benzodioxaphosphorin, 2-octyl-, 2-oxide,2-Octyl-4H-1,3,2-benzodioxaphosphorin-2-one,2-Octyl-2H,4H-1,3,2lambda~5~-benzodioxaphosphinin-2-one
MW : 282.32
Formula : C15H23O3P
CAS_number : 142840-32-2
PubChem : 46238464
UniChem : YTURVHUJFLMJCA-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families :
Stucture :
Protein :
References (8)
| Title : Each lipase has a unique sensitivity profile for organophosphorus inhibitors - Quistad_2006_Toxicol.Sci_91_166 |
| Author(s) : Quistad GB , Liang SN , Fisher KJ , Nomura DK , Casida JE |
| Ref : Toxicol Sci , 91 :166 , 2006 |
| Abstract : Quistad_2006_Toxicol.Sci_91_166 |
| ESTHER : Quistad_2006_Toxicol.Sci_91_166 |
| PubMedSearch : Quistad_2006_Toxicol.Sci_91_166 |
| PubMedID: 16449251 |
| Title : Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets - |
| Author(s) : Casida JE , Quistad GB |
| Ref : Chemical Research in Toxicology , 17 :983 , 2004 |
| PubMedID: 15310231 |
| Title : Localization of [3H]octylphosphonyl-labeled neuropathy target esterase by chicken nervous tissue autoradiography - Kamijima_1999_Neurosci.Lett_273_101 |
| Author(s) : Kamijima M , Casida JE |
| Ref : Neuroscience Letters , 273 :101 , 1999 |
| Abstract : Kamijima_1999_Neurosci.Lett_273_101 |
| ESTHER : Kamijima_1999_Neurosci.Lett_273_101 |
| PubMedSearch : Kamijima_1999_Neurosci.Lett_273_101 |
| PubMedID: 10505626 |
| Title : Organophosphorus neuropathy target esterase inhibitors selectively block outgrowth of neurite-like and cell processes in cultured cells - Li_1998_Toxicol.Lett_98_139 |
| Author(s) : Li W , Casida JE |
| Ref : Toxicol Lett , 98 :139 , 1998 |
| Abstract : Li_1998_Toxicol.Lett_98_139 |
| ESTHER : Li_1998_Toxicol.Lett_98_139 |
| PubMedSearch : Li_1998_Toxicol.Lett_98_139 |
| PubMedID: 9788582 |
| Title : Actions of two highly potent organophosphorus neuropathy target esterase inhibitors in mammalian cell lines - Li_1997_Toxicol.Lett_92_123 |
| Author(s) : Li W , Casida JE |
| Ref : Toxicol Lett , 92 :123 , 1997 |
| Abstract : Li_1997_Toxicol.Lett_92_123 |
| ESTHER : Li_1997_Toxicol.Lett_92_123 |
| PubMedSearch : Li_1997_Toxicol.Lett_92_123 |
| PubMedID: 9295235 |
| Title : Subacute neurotoxicity induced in mice by potent organophosphorus neuropathy target esterase inhibitors - Wu_1996_Toxicol.Appl.Pharmacol_139_195 |
| Author(s) : Wu SY , Casida JE |
| Ref : Toxicology & Applied Pharmacology , 139 :195 , 1996 |
| Abstract : Wu_1996_Toxicol.Appl.Pharmacol_139_195 |
| ESTHER : Wu_1996_Toxicol.Appl.Pharmacol_139_195 |
| PubMedSearch : Wu_1996_Toxicol.Appl.Pharmacol_139_195 |
| PubMedID: 8685903 |
| Title : Neuropathy target esterase of hen brain: active site reactions with 2-[octyl-3H]octyl-4H-1,3,2-benzodioxaphosphorin 2-oxide and 2-octyl-4H-1,3,2-[aryl-3H]benzodioxaphosphorin 2-oxide - Yoshida_1995_J.Neurochem_64_1680 |
| Author(s) : Yoshida M , Tomizawa M , Wu SY , Quistad GB , Casida JE |
| Ref : Journal of Neurochemistry , 64 :1680 , 1995 |
| Abstract : Yoshida_1995_J.Neurochem_64_1680 |
| ESTHER : Yoshida_1995_J.Neurochem_64_1680 |
| PubMedSearch : Yoshida_1995_J.Neurochem_64_1680 |
| PubMedID: 7891095 |