OCP
Adduct covalently bound to the active serine after inhibition by the para nitrophenyl phosphonate and elimination of the paranitrophenyl as leaving group
General
Type : Organophosphate,Triacylglycerol
Chemical_Nomenclature : [(2R)-2,3-bis(octylcarbamoyloxy)propoxy]-octylphosphinic acid
Canonical SMILES : CCCCCCCCNC(=O)OCC(COP(=O)(CCCCCCCC)O)OC(=O)NCCCCCCCC
InChI : InChI=1S\/C29H59N2O7P\/c1-4-7-10-13-16-19-22-30-28(32)36-25-27(38-29(33)31-23-20-17-14-11-8-5-2)26-37-39(34,35)24-21-18-15-12-9-6-3\/h27H,4-26H2,1-3H3,(H,30,32)(H,31,33)(H,34,35)\/t27-\/m1\/s1
InChIKey : QRWKUAOYWKHOGP-HHHXNRCGSA-N
Other name(s) : octyl-phosphinic acid 1,2-bis-octylcarbamoyoxy-ethyl ester,AC1L9I0O,[(2R)-2,3-bis(octylcarbamoyloxy)propoxy]-octylphosphinic acid,Octylphosphonate
MW : 578.76
Formula : C29H59N2O7P
CAS_number :
PubChem : 445454
UniChem : QRWKUAOYWKHOGP-HHHXNRCGSA-N
IUPHAR :
Wikipedia :
Target
Families : OCP ligand of proteins in family: Bacterial_lip_FamI.1 || Bacterial_lip_FamI.2
Stucture :
Protein : pseae-llipa || burce-lipaa
References (2)
| Title : Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases - Nardini_2000_J.Biol.Chem_275_31219 |
| Author(s) : Nardini M , Lang DA , Liebeton K , Jaeger KE , Dijkstra BW |
| Ref : Journal of Biological Chemistry , 275 :31219 , 2000 |
| Abstract : Nardini_2000_J.Biol.Chem_275_31219 |
| ESTHER : Nardini_2000_J.Biol.Chem_275_31219 |
| PubMedSearch : Nardini_2000_J.Biol.Chem_275_31219 |
| PubMedID: 10893416 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Structural basis of the chiral selectivity of Pseudomonas cepacia lipase - Lang_1998_Eur.J.Biochem_254_333 |
| Author(s) : Lang DA , Mannesse ML , De Haas GH , Verheij HM , Dijkstra BW |
| Ref : European Journal of Biochemistry , 254 :333 , 1998 |
| Abstract : Lang_1998_Eur.J.Biochem_254_333 |
| ESTHER : Lang_1998_Eur.J.Biochem_254_333 |
| PubMedSearch : Lang_1998_Eur.J.Biochem_254_333 |
| PubMedID: 9660188 |
| Gene_locus related to this paper: burce-lipaa |