Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: PSK

General
Type Organophosphate
Chemical_Nomenclature [(3R,4S)-4-hydroxy-3-methyl-2-oxohexyl]phosphinic acid
Canonical SMILES CCC(C(C)C(=O)CP(=O)O)O
InChI InChI=1S/C7H15O4P/c1-3-6(8)5(2)7(9)4-12(10)11/h5-6,8,12H,3-4H2,1-2H3,(H,10,11)/t5-,6+/m1/s1
InChIKey UXHVQAJQXZWLAW-RITPCOANSA-N
Other name(s) PSK ; DB08431
________________________________________________________________________________________________
MW|194.16
Formula|C7H15O4P
CAS_number|
PubChem|46937177
UniChem|UXHVQAJQXZWLAW-RITPCOANSA-N
IUPHAR|
Wikipedia|

Target
Families | PSK ligand of proteins in family: Thioesterase
Stucture | 1 structure: 2H7Y: Pikromycin Thioesterase with covalent affinity label
Protein | strve-PIKAIV

References:
Search PubMed for references concerning: PSK
    Title: Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels
    Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA
    Ref: Nat Chemical Biology, 2:531, 2006 : PubMed