Palmitoleic-acid
Palmitoleic acid, or 9-hexadecenoic acid, is an unsaturated fatty acid that is a common constituent of the glycerides of human adipose tissue. Present in all tissues, generally found in higher concentrations in the liver. Macadamia oil (Macadamia integrifolia) and Sea Buckthorn oil (Hippophae rhamnoides) are botanical sources of palmitoleic acid, containing 22 and 40% respectively . Palmitoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism || . Product of hydrolysis of Wnt acylated protein IC50 471 microM
General
Type : Natural,Fatty acid
Chemical_Nomenclature : (Z)-hexadec-9-enoic acid
Canonical SMILES : CCCCCCC=CCCCCCCCC(=O)O
InChI : InChI=1S\/C16H30O2\/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18\/h7-8H,2-6,9-15H2,1H3,(H,17,18)\/b8-7-
InChIKey : SECPZKHBENQXJG-FPLPWBNLSA-N
Other name(s) : Palmitoleic acid,Cis-9-Hexadecenoic acid,(Z)-Hexadec-9-enoic acid,9-cis-Hexadecenoic acid,Zoomaric acid,PAM
MW : 254.41
Formula : C16H30O2
CAS_number : 373-49-9
PubChem : 445638
UniChem : SECPZKHBENQXJG-FPLPWBNLSA-N
IUPHAR :
Wikipedia : Palmitoleic_acid
Target
Families : Palmitoleic-acid ligand of proteins in family: Pectinacetylesterase-Notum
Stucture : 4UZQ Structure of th humane wnt deacetylase notum in complex with O-Palmitoleoyl serine- Crystal form IX - 1.5A
Protein : human-NOTUM
References (1)
| Title : Notum deacylates Wnt proteins to suppress signalling activity - Kakugawa_2015_Nature_519_187 |
| Author(s) : Kakugawa S , Langton PF , Zebisch M , Howell SA , Chang TH , Liu Y , Feizi T , Bineva G , O'Reilly N , Snijders AP , Jones EY , Vincent JP |
| Ref : Nature , 519 :187 , 2015 |
| Abstract : Kakugawa_2015_Nature_519_187 |
| ESTHER : Kakugawa_2015_Nature_519_187 |
| PubMedSearch : Kakugawa_2015_Nature_519_187 |
| PubMedID: 25731175 |
| Gene_locus related to this paper: drome-q9vux3 , human-NOTUM |