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Inhibitor Report for: Permethrin

Not an inhibitor. See Permethrin as substrate Permethrin The target is prolonging sodium channel activation. Only few Pyrethroids interact with carboxylesterases. Pyrethrins are naturally-occurring compounds with insecticidal properties that are found in pyrethrum extract from certain chrysanthemum flowers. The pyrethrins are often used in household insecticides and products to control insects on pets or livestock. Pyrethroids are manufactured chemicals that are very similar in structure to the pyrethrins, but are often more toxic to insects as well as to mammals, and last longer in the environment than the pyrethrins.


General
Type Pyrethroid, Insecticide, Not A/B H target, Phenoxyphenyl, Cyclopropane
Chemical_Nomenclature (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
Canonical SMILES CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
InChI InChI=1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3
InChIKey RLLPVAHGXHCWKJ-UHFFFAOYSA-N
Other name(s) Transpermethrin ; Ambush ; Pounce ; 1RS,cis-Permethrin ; Permethrine ; Ambushfog ; Chinetrin ; Efmethrin ; Imperator ; Indothrin ; Outflank ; Permasect ; Perthrine ; Ectiban ; FMC 33297 ; BW-21-Z ; Eksmin ; Kafil ; Pramex ; Talcord ; Nix ; Dragnet
________________________________________________________________________________________________
MW|391.29
Formula|C21H20Cl2O3
CAS_number|52645-53-1
PubChem|40326
UniChem|RLLPVAHGXHCWKJ-UHFFFAOYSA-N
IUPHAR|
Wikipedia|Permethrin

Target

References:
Search PubMed for references concerning: Permethrin

8 more
    Title: Isolation and identification of an esterase from a Mexican strain of Boophilus microplus (Acari: Ixodidae)
    Pruett JH, Guerrero FD, Hernandez R
    Ref: J Econ Entomol, 95:1001, 2002 : PubMed

            

    Title: Influence of permethrin, diazinon and ivermectin treatments on insecticide resistance in the horn fly (Diptera: Muscidae)
    Byford RL, Craig ME, DeRouen SM, Kimball MD, Morrison DG, Wyatt WE, Foil LD
    Ref: International Journal for Parasitology, 29:125, 1999 : PubMed

            

    Title: Insecticide susceptibility in mosquitoes (Diptera: Culicidae) from French Polynesia
    Failloux AB, Ung A, Raymond M, Pasteur N
    Ref: Journal of Medical Entomology, 31:639, 1994 : PubMed