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Inhibitor Report for: R-Pro-(decarboxy-Pro)-X97

General
Type Pyrrolidine, Imidazole
Chemical_Nomenclature 3-[4-oxo-4-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butyl]-5,5-diphenylimidazolidine-2,4-dione
Canonical SMILES C1CCN(C1)C(=O)C2CCCN2C(=O)CCCN3C(=O)C(NC3=O)(C4=CC=CC=C4)C5=CC=CC=C5
InChI InChI=1S/C28H32N4O4/c33-24(31-19-9-15-23(31)25(34)30-17-7-8-18-30)16-10-20-32-26(35)28(29-27(32)36,21-11-3-1-4-12-21)22-13-5-2-6-14-22/h1-6,11-14,23H,7-10,15-20H2,(H,29,36)/t23-/m0/s1
InChIKey PHYVMRFCTLZIHY-QHCPKHFHSA-N
Other name(s) CHEMBL516159 ; 3-{4-Oxo-4-[(2s)-2-(Pyrrolidin-1-Ylcarbonyl)pyrrolidin-1-Yl]butyl}-5,5-Diphenylimidazolidine-2,4-Dione ; 3eq9 ; BDBM50275012 ; 3-{4-Oxo-4-[(2S)-2-(pyrrolidinocarbonyl)pyrrolidin-1-yl]butyl}-5,5-diphenylimidazolidine-2,4-dione ; X97
________________________________________________________________________________________________
MW|488.58
Formula|C28H32N4O4
CAS_number|
PubChem|25155838
UniChem|PHYVMRFCTLZIHY-QHCPKHFHSA-N
IUPHAR|
Wikipedia|

Target
Families | R-Pro-(decarboxy-Pro)-X97 ligand of proteins in family: S9N_PPCE_Peptidase_S9
Stucture | 1 structure: 3EQ9: Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors 3
Protein | pig-ppce

References:
Search PubMed for references concerning: R-Pro-(decarboxy-Pro)-X97
    Title: Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules
    Kannai K, Aranyi P, Bocskei Z, Ferenczy G, Harmat V, Simon K, Batori S, Naray-Szabo G, Hermecz I
    Ref: Journal of Medicinal Chemistry, 51:7514, 2008 : PubMed