Inhibitor

Bibliography

Biblio print

Tree Display

AceDB Schema

XML Display

Feedback

Inhibitor Report for: Rh-pNP

The incorporation of a synthetic, catalytically competent metallo cofactor into a protein scaffold to generate an artificial metalloenzyme (ArM) lead to new activities specific of the cofactor. The new enzymes show racemization of (S)-1-phenylethanol and selective acylation of 1-phenylethanol


General
Type Organophosphate, Pincer-Metal-cofactor, pNP
Chemical_Nomenclature
Canonical SMILES
InChI
InChIKey
Other name(s)
________________________________________________________________________________________________
MW|815.20
Formula|C39H55ClN3O5PRh
CAS_number|
PubChem|
UniChem|
IUPHAR|
Wikipedia|

Target
Families | Rh-pNP ligand of proteins in family: Canar_LipB, Cutinase
Protein | canar-LipB, fusso-cutas

References:
Search PubMed for references concerning: Rh-pNP
    Title: Lipase active site covalent anchoring of Rh(NHC) catalysts: towards chemoselective artificial metalloenzymes
    Basauri-Molina M, Riemersma CF, Wurdemann MA, Kleijn H, Klein Gebbink RJ
    Ref: Chem Commun (Camb), 51:6792, 2015 : PubMed