SXC
The incorporation of a synthetic, catalytically competent metallo cofactor into a protein scaffold to generate an artificial metalloenzyme (ArM) lead to new activities specific of the cofactor
General
Type : Organophosphate,Pincer-Metal-cofactor,pNP,Sulfur Compound
Chemical_Nomenclature : bromopalladium(1+)\;[3-[3-[ethoxy(hydroxy)phosphoryl]propyl]-5-(methylsulfoniomethyl)benzene-6-id-1-yl]methyl-methylsulfanium
Canonical SMILES : CCOP(=O)(CCCC1=CC(=[C-]C(=C1)C[SH+]C)C[SH+]C)O.Br[Pd+]
InChI : InChI=1S\/C15H24O3PS2.BrH.Pd\/c1-4-18-19(16,17)7-5-6-13-8-14(11-20-2)10-15(9-13)12-21-3\;\;\/h8-9H,4-7,11-12H2,1-3H3,(H,16,17)\;1H\;\/q-1\;\;+2\/p+1
InChIKey : SIFSBFIBXYYZCT-UHFFFAOYSA-O
Other name(s) : NCN-Pd-Pincer,SXC
MW : 535.78
Formula : C15H26BrO3PPdS2+2
CAS_number :
PubChem : 44129616
UniChem : SIFSBFIBXYYZCT-UHFFFAOYSA-O
IUPHAR :
Wikipedia :
Target
References (2)
| Title : Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids - Rutten_2009_Chemistry_15_4270 |
| Author(s) : Rutten L , Wieczorek B , Mannie JP , Kruithof CA , Dijkstra HP , Egmond MR , Lutz M , Klein Gebbink RJ , Gros P , van Koten G |
| Ref : Chemistry , 15 :4270 , 2009 |
| Abstract : Rutten_2009_Chemistry_15_4270 |
| ESTHER : Rutten_2009_Chemistry_15_4270 |
| PubMedSearch : Rutten_2009_Chemistry_15_4270 |
| PubMedID: 19219875 |
| Gene_locus related to this paper: fusso-cutas |
| Title : Lipase active-site-directed anchoring of organometallics: metallopincer\/protein hybrids - Kruithof_2005_Chemistry_11_6869 |
| Author(s) : Kruithof CA , Casado MA , Guillena G , Egmond MR , van der Kerk-van Hoof A , Heck AJ , Klein Gebbink RJ , van Koten G |
| Ref : Chemistry , 11 :6869 , 2005 |
| Abstract : Kruithof_2005_Chemistry_11_6869 |
| ESTHER : Kruithof_2005_Chemistry_11_6869 |
| PubMedSearch : Kruithof_2005_Chemistry_11_6869 |
| PubMedID: 16224766 |
| Gene_locus related to this paper: fusso-cutas |