Sulfonamide-D1C
General
Type : Sulfur Compound,Sulfonamide,Trifluoro,Benzenesulfonamide
Chemical_Nomenclature : 4-[[[(2R)-2-amino-3-(2,4,5-trifluorophenyl)propyl]sulfamoylamino]methyl]benzenesulfonamide
Canonical SMILES : C1=CC(=CC=C1CNS(=O)(=O)NCC(CC2=CC(=C(C=C2F)F)F)N)S(=O)(=O)N
InChI : InChI=1S\/C16H19F3N4O4S2\/c17-14-7-16(19)15(18)6-11(14)5-12(20)9-23-29(26,27)22-8-10-1-3-13(4-2-10)28(21,24)25\/h1-4,6-7,12,22-23H,5,8-9,20H2,(H2,21,24,25)\/t12-\/m1\/s1
InChIKey : DJEOZKIXGQHLQG-GFCCVEGCSA-N
Other name(s) : 4-[({[(2r)-2-Amino-3-(2,4,5-Trifluorophenyl)propyl]sulfamoyl}amino)methyl]benzenesulfonamide,D1C
MW : 452.46
Formula : C16H19F3N4O4S2
CAS_number :
PubChem : 70702292
UniChem : DJEOZKIXGQHLQG-GFCCVEGCSA-N
IUPHAR :
Wikipedia :
Target
Families : Sulfonamide-D1C ligand of proteins in family: DPP4N_Peptidase_S9
Stucture : 4DSA Crystal Structure of DPP-IV with Compound C1
Protein : human-DPP4
References (1)
| Title : Design and synthesis of 4-(2,4,5-trifluorophenyl)butane-1,3-diamines as dipeptidyl peptidase IV inhibitors - Zhu_2013_ChemMedChem_8_1104 |
| Author(s) : Zhu L , Li Y , Qiu L , Su M , Wang X , Xia C , Qu Y , Li J , Xiong B , Shen J |
| Ref : ChemMedChem , 8 :1104 , 2013 |
| Abstract : Zhu_2013_ChemMedChem_8_1104 |
| ESTHER : Zhu_2013_ChemMedChem_8_1104 |
| PubMedSearch : Zhu_2013_ChemMedChem_8_1104 |
| PubMedID: 23671024 |
| Gene_locus related to this paper: human-DPP4 |