Suronacrine

Has weaker anticholinesterase actions that are masked by cholinoceptor blockade

General

Type : Acridine

Chemical_Nomenclature : 9-benzylamino-1,2,3,4-tetrahydroacridin-1-ol maleate \; 1-Acridinol, 1,2,3,4-tetrahydro-9-((phenylmethyl)amino)-

Canonical SMILES : C1CC(C2=C(C3=CC=CC=C3N=C2C1)NCC4=CC=CC=C4)O

InChI : InChI=1S\/C20H20N2O\/c23-18-12-6-11-17-19(18)20(15-9-4-5-10-16(15)22-17)21-13-14-7-2-1-3-8-14\/h1-5,7-10,18,23H,6,11-13H2,(H,21,22)

InChIKey : HERUZAOANPGYSY-UHFFFAOYSA-N

Other name(s) : Suronacrinum,HOE-427,HP-128


MW : 304.386

Formula : C20-H20-N2-O

CAS_number : 104675-35-6

PubChem : 60601

UniChem : HERUZAOANPGYSY-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : Suronacrine ligand of proteins in family: ACHE

Stucture :

Protein :

References (1)

Title : Effects of tacrine, velnacrine (HP029), suronacrine (HP128), and 3,4-diaminopyridine on skeletal neuromuscular transmission in vitro - Braga_1991_Br.J.Pharmacol_102_909
Author(s) : Braga MF , Harvey AL , Rowan EG
Ref : British Journal of Pharmacology , 102 :909 , 1991
Abstract : Braga_1991_Br.J.Pharmacol_102_909
ESTHER : Braga_1991_Br.J.Pharmacol_102_909
PubMedSearch : Braga_1991_Br.J.Pharmacol_102_909
PubMedID: 1649660