TMR-T5
General
Type : HaloTag-ligand,Sulfur Compound,Sulfonamide,Xanthene
Chemical_Nomenclature : [9-[2-carboxy-5-[2-[2-[5-(trifluoromethylsulfonylamino)pentoxy]ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium
Canonical SMILES : CN(C)c1ccc2c(c1)OC3=CC(=[N+](C)C)C=CC3=C2c4cc(ccc4C(=O)O)C(=O)NCCOCCOCCCCCNS(=O)(=O)C(F)(F)F
InChI : InChI=1S\/C35H41F3N4O8S\/c1-41(2)24-9-12-27-30(21-24)50-31-22-25(42(3)4)10-13-28(31)32(27)29-20-23(8-11-26(29)34(44)45)33(43)39-15-17-49-19-18-48-16-7-5-6-14-40-51(46,47)35(36,37)38\/h8-13,20-22,40H,5-7,14-19H2,1-4H3,(H-,39,43,44,45)\/p+1
InChIKey : QNUHBXCAJKIQSP-UHFFFAOYSA-O
Other name(s) : IYI
MW : 735.79
Formula : C35H42F3N4O8S
CAS_number :
PubChem : 166625058
UniChem : QNUHBXCAJKIQSP-UHFFFAOYSA-O
IUPHAR :
Wikipedia :
Target
Families : TMR-T5 ligand of proteins in family: Haloalkane_dehalogenase-HLD2
Stucture : 7ZIY X-ray structure of the haloalkane dehalogenase HaloTag7 bound to a pentyltrifluoromethanesulfonamide tetramethylrhodamine ligand (TMR-T5)
Protein : rhoso-halo1
References (1)
| Title : Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy - Kompa_2023_J.Am.Chem.Soc_145_3075 |
| Author(s) : Kompa J , Bruins J , Glogger M , Wilhelm J , Frei MS , Tarnawski M , x , Este E , Heilemann M , Hiblot J , Johnsson K |
| Ref : Journal of the American Chemical Society , 145 :3075 , 2023 |
| Abstract : Kompa_2023_J.Am.Chem.Soc_145_3075 |
| ESTHER : Kompa_2023_J.Am.Chem.Soc_145_3075 |
| PubMedSearch : Kompa_2023_J.Am.Chem.Soc_145_3075 |
| PubMedID: 36716211 |
| Gene_locus related to this paper: rhoso-halo1 |