Tetrahydrolipstatin-alkyne
General
Type : Oxooxetan,Lipase inhibitor,Alkyne
Chemical_Nomenclature :
Canonical SMILES : CCCCCCCCCCCC(CC1OC(C1CCCCC#C)=O)OC(=O)C(NC(=O)[H])CC(C)C
InChI : InChI=1S\/C29H49NO5\/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2\/h2,22-27H,5,7-21H2,1,3-4H3,(H,30,31)
InChIKey : YHKLBWUOXJBAIG-UHFFFAOYSA-N
Other name(s) : Tetrahydrolipstatin (THL)-alkyne,THL-alkyne,Orlistat-alkyne
MW : 491.71
Formula : C29H49NO5
CAS_number :
PubChem :
UniChem : YHKLBWUOXJBAIG-UHFFFAOYSA-N
IUPHAR :
Wikipedia :
Target
Families : Tetrahydrolipstatin-alkyne ligand of proteins in family: Hormone-sensitive_lipase_like
Stucture :
Protein : myctu-Rv2970c
References (1)
| Title : Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL) - Ravindran_2014_Mol.Cell.Proteomics_13_435 |
| Author(s) : Ravindran MS , Rao SP , Cheng X , Shukla A , Cazenave-Gassiot A , Yao SQ , Wenk MR |
| Ref : Mol Cell Proteomics , 13 :435 , 2014 |
| Abstract : Ravindran_2014_Mol.Cell.Proteomics_13_435 |
| ESTHER : Ravindran_2014_Mol.Cell.Proteomics_13_435 |
| PubMedSearch : Ravindran_2014_Mol.Cell.Proteomics_13_435 |
| PubMedID: 24345785 |
| Gene_locus related to this paper: myctu-Rv2970c |